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Discovery and confirmation of a protein biomarker panel with potential to predict response to biological therapy in psoriatic arthritis.

Author: AdemowoOpeyemi S, CollinsEmily, FearonUrsula, FitzGeraldOliver, GerlagDanielle M, HernandezBelinda, PenningtonStephen R, RooneyCathy, TakPaul-P, van KuijkArno W

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

While biological medications can be effective for psoriatic arthritis (PsA), they are expensive and can cause side effects. This study aims to identify specific proteins in the blood that could predict which patients with PsA will respond well to biological treatments.
Paper Details　
Original Abstract of the Article :
Biological therapies, which include antitumour necrosis factor-α and T-cell inhibitors, are potentially effective treatments for psoriatic arthritis (PsA) but are costly and may induce a number of side effects. Response to treatment in PsA is variable and difficult to predict. Here, we sought to ide...See full text at original site
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引用元：
https://doi.org/10.1136/annrheumdis-2014-205417

データ提供：米国国立医学図書館（NLM）

Unlocking the Mystery of Psoriatic Arthritis: A Biomarker Panel for Predicting Treatment Response

Psoriatic arthritis (PsA) is a chronic inflammatory condition that can significantly impact quality of life. This study, published in [journal name], dives into the world of [rheumatology] and explores a new avenue for personalized medicine in PsA treatment.

The authors sought to identify a panel of protein biomarkers that could predict which PsA patients would respond to biological therapies, such as anti-TNF-α and T-cell inhibitors.

The study, although still in the discovery phase, identifies a potential protein biomarker panel that could be used to predict the response to biologic treatment. The authors believe this research could have significant implications for personalized medicine in PsA treatment, allowing for more effective and targeted therapies.

Personalized Medicine: A Path to Precision

The study's findings pave the way for a more personalized approach to PsA treatment. This research is a stepping stone towards a future where treatments are tailored to individual patients, maximizing efficacy and minimizing side effects.

The Power of Biomarkers: Navigating the Desert of Disease

This study provides a compelling case for the power of biomarkers in understanding disease and guiding treatment. The potential to use biomarkers to predict treatment response could revolutionize the care of PsA patients.

Dr. Camel's Conclusion

The study's findings offer a glimmer of hope in the desert of PsA research. This research is a testament to the power of science and the potential to personalize medicine, offering a more precise and effective approach to treating this challenging condition.

Date :
  1. Date Completed 2016-04-06
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

25187158

DOI: Digital Object Identifier

10.1136/annrheumdis-2014-205417

Related Literature

Article Analysis
・Effective treatment of psoriatic arthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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