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Percutaneous transluminal angioplasty versus operation for peripheral arteriosclerosis. Report of a prospective randomized trial in a selected group of patients.

Author: CrossA P, WilsonS E, WolfG L

Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study compared percutaneous transluminal angioplasty (PTA) with surgery for treating blocked blood vessels in the legs. 255 patients were randomized to receive either treatment. PTA had a 15.5% immediate failure rate, while surgery had a 0.8% in-hospital death rate and 13.5% complication rate. Over 4.5 years, both groups experienced similar rates of death (20%) and major leg amputations (10%). While surgery resulted in a slightly greater improvement in blood flow immediately after treatment, both groups showed similar long-term improvement in blood flow.
Paper Details　
Original Abstract of the Article :
A prospective, randomized comparison of percutaneous transluminal angioplasty (PTA) with surgery in the treatment of occlusive disease of the iliac, superficial femoral, or popliteal arteries began in 1983. Radiologists and vascular surgeons independently assessed index lesions on arteriograms to de...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2521362

データ提供：米国国立医学図書館（NLM）

Percutaneous Transluminal Angioplasty Versus Operation for Peripheral Arteriosclerosis

This prospective, randomized trial compares percutaneous transluminal angioplasty (PTA) with surgery in treating occlusive disease of the iliac, superficial femoral, or popliteal arteries. The study found that PTA achieved comparable hemodynamic improvement and durability to surgery, despite a higher immediate failure rate. The authors conclude that PTA offers a viable alternative to surgery in treating peripheral arteriosclerosis, particularly for patients with less severe disease.

PTA: A Viable Alternative to Surgery for Peripheral Arteriosclerosis

This research provides valuable insights into the effectiveness of percutaneous transluminal angioplasty (PTA) as a treatment option for peripheral arteriosclerosis. The study found that PTA achieved comparable hemodynamic improvement and durability to surgery, demonstrating its viability as an alternative approach, particularly for patients with less severe disease. This research contributes to the development of less invasive and more patient-friendly treatment options for peripheral arteriosclerosis.

Minimizing Invasive Procedures and Improving Patient Outcomes

This research emphasizes the importance of exploring less invasive treatment options for peripheral arteriosclerosis. The study's findings demonstrate the efficacy of percutaneous transluminal angioplasty (PTA) as a viable alternative to surgery, offering a less invasive and potentially more patient-friendly approach. This research encourages a shift toward less invasive procedures, promoting improved patient outcomes and reduced healthcare costs.

Dr. Camel's Conclusion

Just as a camel can navigate through a challenging desert landscape by adapting its gait and seeking out the most efficient path, healthcare professionals must be adaptable in their approach to treatment. This research demonstrates the efficacy of percutaneous transluminal angioplasty (PTA) as a less invasive alternative to surgery for peripheral arteriosclerosis. By embracing innovation and exploring less invasive treatment options, we can improve patient outcomes and enhance the effectiveness of healthcare, just as a skilled camel navigates its way through the desert landscape.

Date :
  1. Date Completed 1989-02-15
  2. Date Revised 2012-10-03
Further Info :

Pubmed ID

2521362

DOI: Digital Object Identifier

0741-5214(89)90213-9

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Languages

English

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