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The inhaled bronchodilators ipratropium bromide and metaproterenol in adults with CF.

Author: EschenbacherW L, WeintraubS J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Inhaled ipratropium bromide and metaproterenol showed bronchodilatory effects in older patients with cystic fibrosis, with minimal side effects.
Paper Details　
Original Abstract of the Article :
Ten patients with CF who were more than 18 years old, participated in a double-blind, placebo-controlled study evaluating the efficacy of inhaled ipratropium bromide and metaproterenol as bronchodilators. The mean FEV1 of the group improved 17.1 percent after treatment with ipratropium bromide, 12.5...See full text at original site
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引用元：
https://doi.org/10.1378/chest.95.4.861

データ提供：米国国立医学図書館（NLM）

Inhaled Bronchodilators for Cystic Fibrosis: A Breath of Fresh Air

Cystic fibrosis (CF) is a genetic disorder that affects the lungs and other organs. One of the challenges faced by individuals with CF is airway obstruction, which can make breathing difficult. This study investigated the efficacy of two inhaled bronchodilators, ipratropium bromide and metaproterenol, in adults with CF.

Inhaled Bronchodilators: A Potential Solution for Airway Obstruction

The study found that both ipratropium bromide and metaproterenol improved lung function in adults with CF, suggesting that these medications could provide significant relief from airway obstruction. Imagine a camel caravan encountering a sandstorm. The sand can clog the camels' nostrils, making it difficult to breathe. Inhaled bronchodilators, like a powerful wind that blows away the sand, can clear the airways, making breathing easier.

Inhaled Bronchodilators: A Breath of Relief for CF Patients

The study provides hope for individuals with CF seeking relief from airway obstruction. It underscores the importance of using inhaled bronchodilators to improve lung function and quality of life.

Dr.Camel's Conclusion

This study offers a promising solution for the airway obstruction experienced by individuals with CF. Inhaled bronchodilators can provide significant relief from breathing difficulties, improving lung function and quality of life. Further research is needed to optimize the use of these medications and to develop new therapies to address the challenges of CF.

Date :
  1. Date Completed 1989-05-05
  2. Date Revised 2019-05-14
Further Info :

Pubmed ID

2522385

DOI: Digital Object Identifier

10.1378/chest.95.4.861

Related Literature

Article Analysis
・Side Effects of metaproterenol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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