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Superiority of ivermectin 1% cream over metronidazole 0·75% cream in treating inflammatory lesions of rosacea: a randomized, investigator-blinded trial.
Author: , Berth-JonesJ, JacovellaJ, OrtonneJ P, PeironeM H, RoszkiewiczJ, RuzickaT, TaiebA
Original Abstract of the Article :
BACKGROUND: Few therapeutic alternatives currently exist in the treatment of papulopustular rosacea (PPR). OBJECTIVES: To demonstrate superiority of once-daily ivermectin 1% cream (IVM 1%) once daily vs. twice-daily metronidazole (MTZ 0·75%) cream, regarding percentage reduction of inflammatory les...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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引用元:
https://doi.org/10.1111/bjd.13408
データ提供:米国国立医学図書館(NLM)
Ivermectin vs. Metronidazole for Rosacea: A Camel's Tale of Two Treatments
The treatment of [papulopustular rosacea (PPR)] can be a challenging endeavor, requiring effective and well-tolerated therapies. This study compares the efficacy of [ivermectin 1% cream] to [metronidazole 0.75% cream] in treating moderate to severe PPR. The researchers conducted a [Phase 3, investigator-blinded, randomized, parallel-group study] and found that [ivermectin 1% cream was significantly superior to metronidazole 0.75% cream] in reducing inflammatory lesions, with improvement observed as early as week 3. Additionally, [ivermectin 1% cream demonstrated better local tolerability] than metronidazole.
A Camel's Oasis: Finding Relief from Rosacea
Imagine a desert traveler battling a persistent skin irritation. Two different ointments are offered, one providing a more effective and soothing relief. This analogy represents the study's findings, where ivermectin 1% cream emerged as the more effective and better-tolerated treatment for rosacea. This discovery brings hope for individuals seeking a more successful and comfortable path to managing their skin condition.
A Camel's Word of Encouragement
As a camel who has traversed the desert's harsh landscapes, I know the importance of finding the right treatment for skin conditions. While this study suggests the effectiveness of ivermectin 1% cream, it's essential to consult with a dermatologist to determine the best course of action for your individual needs. Remember, taking care of your skin is a crucial step in maintaining overall health and well-being.
Dr. Camel's Conclusion
Ivermectin 1% cream emerges as a beacon of hope for those seeking relief from the fiery sands of rosacea. Its superior efficacy and better tolerability offer a more comfortable and effective journey toward clear skin. While it might not be a universal solution, it represents a significant step forward in managing this common condition.
Date :
- Date Completed 2016-01-04
- Date Revised 2022-04-08
Further Info :
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