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Weight-loss therapy in type 2 diabetes: effects of phentermine and topiramate extended release.

Author: BohannonNancy J V, DvorakRoman V, GarveyW Timothy, KushnerRobert F, RuegerMiriam, RyanDonna H, TroupinBarbara

Clinical Trial, Phase IIA Phase II trial is a trial that further evaluates the efficacy and safety of a new drug or treatment, whose safety has been confirmed to some extent in a Phase I trial, in a small number of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study assesses the safety and efficacy of phentermine/topiramate extended-release (ER) plus lifestyle modification for weight loss and glycemic control in obese or overweight adults with type 2 diabetes. The study found that the combination therapy was associated with significant weight loss and improvements in glycemic control.
Paper Details　
Original Abstract of the Article :
Treatment algorithms for type 2 diabetes recommend weight loss for disease management. The safety and efficacy of treatment with phentermine (PHEN)/topiramate (TPM) extended release (ER) plus lifestyle modification for weight loss and glycemic benefits were assessed in two randomized, double-blind, ...See full text at original site
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引用元：
https://doi.org/10.2337/dc14-0930

データ提供：米国国立医学図書館（NLM）

The Quest for Weight Loss in Type 2 Diabetes

Type 2 diabetes, a prevalent health concern, often necessitates weight management as a crucial component of treatment. This research investigates the effectiveness of a novel approach to weight loss in individuals with type 2 diabetes. The study utilizes [research method] to evaluate the [key objective]. This exploration reveals [key finding], offering a potential avenue for managing weight and improving glycemic control in individuals with type 2 diabetes. This study underscores the importance of personalized approaches to weight management in this complex disease.

A New Path Through the Desert of Weight Management

The research highlights a potential solution for tackling the challenges of weight management in individuals with type 2 diabetes. The study's findings demonstrate [key finding]. This discovery could lead to more effective and personalized weight management strategies, potentially improving the overall health and well-being of individuals with type 2 diabetes.

The Oasis of Health: Managing Weight in Type 2 Diabetes

Weight management, like finding a life-giving oasis in the desert of type 2 diabetes, is a critical aspect of health. This study provides valuable insights into this crucial area, highlighting [key recommendation]. By adopting these strategies, individuals with type 2 diabetes can potentially improve their health and navigate the challenging journey of weight management with greater success.

Dr.Camel's Conclusion

This research provides a valuable roadmap for navigating the complex terrain of weight management in individuals with type 2 diabetes. The study's findings emphasize the importance of personalized approaches that combine lifestyle modifications with effective medications, potentially leading to significant improvements in glycemic control and overall health.

Date :
  1. Date Completed 2015-06-16
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

25249652

DOI: Digital Object Identifier

10.2337/dc14-0930

Related Literature

Article Analysis
・Effects of phentermine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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