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Dietary supplements for chronic gout.
Author: AndrésMariano, BuchbinderRachelle, CarmonaLoreto, FalzonLouise, SiveraFrancisca
Original Abstract of the Article :
BACKGROUND: Dietary supplements are frequently used for the treatment of several medical conditions, both prescribed by physicians or self administered. However, evidence of benefit and safety of these supplements is usually limited or absent. OBJECTIVES: To assess the efficacy and safety of dietar...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1002/14651858.CD010156.pub2
データ提供:米国国立医学図書館(NLM)
Dietary Supplements: A Journey Through Gout
The realm of dietary supplements in [rheumatology] is a vast desert of possibilities, but often lacks clear oases of evidence. This study, like a weary traveler, embarks on a quest to assess the efficacy and safety of dietary supplements for individuals grappling with the fiery pain of [chronic gout]. The researchers utilized a [systematic review] approach, meticulously combing through [Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE and CINAHL] for relevant [randomized controlled trials (RCTs) or quasi-RCTs]. Their aim was to decipher the impact of these supplements on [frequency of gouty attacks, pain reduction, health-related quality of life, serum uric acid (sUA) normalisation, function (i.e. activity limitation), tophus regression, and the rate of serious adverse events].
A Glimpse into the Results
The results, like a mirage in the desert, shimmer with uncertainty. The study unearthed two trials, each focusing on different supplements, [enriched skim milk powder (SMP) and vitamin C], and distinct outcomes. The first trial, a moderately sized expedition with [120 participants], explored the effects of SMP fortified with [glycomacropeptides (GMP)] compared to plain SMP and lactose powder. The findings indicated a potential reduction in the frequency of gout flares, but the evidence, like a distant oasis, was quite hazy. The second trial, a smaller expedition with [40 participants], compared the effects of vitamin C to the well-established [allopurinol]. While vitamin C showed a glimmer of hope in reducing [sUA], it was not as potent as its pharmaceutical counterpart, allopurinol.
Navigating the Landscape of Dietary Supplements
This study highlights the need for more robust research in this field. It's like exploring a vast desert with only a few flickering candles to guide our way. We must navigate the complexities of [gout] and the potential benefits and risks of dietary supplements with caution. These findings serve as a reminder that dietary supplements should not be considered a replacement for conventional treatments. The authors, like seasoned travelers, emphasize the importance of consulting with a qualified healthcare professional to discuss the potential benefits and risks of dietary supplements, especially when managing [gout].
Dr.Camel's Conclusion
The desert of dietary supplements for gout is vast and mysterious. This study, like a lone camel caravan, shed some light on the potential benefits and risks of these supplements. While the findings are promising, more research is needed to provide a clearer picture. We must remember, just as a camel carefully navigates the treacherous desert sands, we must approach dietary supplements with a discerning eye and a healthy dose of skepticism. The quest for knowledge in this field continues, and like the desert, it holds both challenges and rewards.
Date :
- Date Completed 2014-12-19
- Date Revised 2021-12-03
Further Info :
Related Literature
English
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