Effective treatment of dietary supplements: A Synthesis of Findings from 15 Studies

  1. Home
  2. Effective treatment of dietary supplements
This information is not medical advice and is not a substitute for diagnosis or treatment by a physician.Data sources and disclaimers (data limitations, copyright, etc.)The analysis on "Effective treatment of dietary supplements: A Synthesis of Findings from 15 Studies" on this page is based on PubMed data provided by the U.S. National Library of Medicine (NLM). However, NLM does not endorse or verify these analyses.

This analysis is based on research papers included in PubMed, but medical research is constantly evolving and may not fully reflect the latest findings. There may also be biases towards certain research areas.

This information is not medical advice and is not a substitute for diagnosis or treatment by a physician. If you have concerns about "Effective treatment of dietary supplements: A Synthesis of Findings from 15 Studies", please consult your doctor.

For NLM copyright information, please see Link to NLM Copyright Page
PubMed data is obtained via Hugging Face Datasets: Link to DatasetPlease check the disclaimer.
This page's analysis is based on PubMed data provided by the U.S. National Library of Medicine (NLM).
Original Abstract of the Article

Major Research Findings

Dietary supplements are frequently used to treat various medical conditions, including gout. However, the evidence for their benefits and safety is often limited or absent. 1 , 3

Existing research has investigated the use of dietary supplements such as glycomacropeptide-enriched skim milk powder (SMP) and vitamin C for gout, but their effectiveness remains uncertain. 1 , 3

One study compared SMP/GMP/G600 with a control group and found no statistically significant differences in gout attack frequency, pain, health-related quality of life, uric acid levels, physical function, or improvement in gout nodules. 1 , 3

Another study showed that vitamin C was less effective than allopurinol in reducing uric acid levels. 1 , 3

These studies fail to provide conclusive evidence supporting the effectiveness of dietary supplements for gout. 1 , 3

Treatment Summary

Glycomacropeptide-enriched skim milk powder (SMP) may potentially reduce gout attack frequency, but its effects are limited, and further research is needed. 1 , 3

Vitamin C is expected to lower uric acid levels, but it's not as effective as allopurinol. 1 , 3

Benefits and Risks

Benefit Summary

Glycomacropeptide-enriched skim milk powder (SMP) may reduce gout attack frequency. 1 , 3

Vitamin C is expected to lower uric acid levels. 1 , 3

Risk Summary

Glycomacropeptide-enriched skim milk powder (SMP) may cause gastrointestinal side effects. 1 , 3

Vitamin C is generally safe as a dietary supplement, but high doses may pose a risk of side effects. 1 , 3

Comparison of Studies

Commonalities

Both studies aimed to investigate the role of dietary supplements in treating gout. 1 , 3

Differences

Study 1 evaluated glycomacropeptide-enriched skim milk powder (SMP), while study 2 assessed vitamin C. 1 , 3

Study 1 evaluated gout attack frequency, pain, health-related quality of life, uric acid levels, physical function, and improvement in gout nodules. 1 , 3

Study 2 assessed the reduction of uric acid levels. 1 , 3

Consistency and Contradictions in Findings

Conclusive evidence supporting the effectiveness of dietary supplements for gout is still lacking. 1 , 3

Glycomacropeptide-enriched skim milk powder (SMP) may potentially reduce gout attack frequency, but its effects are limited, and further research is needed. 1 , 3

Vitamin C is expected to lower uric acid levels, but it's not as effective as allopurinol. 1 , 3

Applying Results to Daily Life: Points to Consider

The effectiveness of dietary supplements for gout remains uncertain. 1 , 3

It is important to consult a doctor and choose appropriate treatment methods under their guidance when considering gout management. 1 , 3

Limitations of Current Research

The number of studies evaluating the effectiveness of dietary supplements for gout is limited, and the findings are insufficient to generalize. 1 , 3

Furthermore, variations in study designs and evaluation criteria make direct comparisons between results challenging. 1 , 3

Future Research Directions

More research is required with a larger number of participants and more rigorous designs to evaluate the effectiveness of dietary supplements for gout. 1 , 3

Further investigation is needed into various combinations of dietary supplements and their effectiveness based on the severity of gout. 1 , 3

Conclusion

The effectiveness of dietary supplements for gout remains uncertain. 1 , 3

It is crucial to consult a doctor and choose appropriate treatment methods under their guidance when considering gout management. 1 , 3

Treatment List

  • Glycomacropeptide-enriched skim milk powder (SMP) 1 , 3
  • Vitamin C 1 , 3
Literature analysis of 15 papers
Positive Content
10
Neutral Content
3
Negative Content
2
Article Type
1
1
3
8
14
1.

Dietary supplements for chronic gout.

Author: AndrésMariano, SiveraFrancisca, FalzonLouise, BuchbinderRachelle, CarmonaLoreto

Gout treatment
Gastrointestinal events

This review of two randomized controlled trials (n=160) investigating the efficacy and safety of dietary supplements for chronic gout found limited evidence. One trial showed a small, uncertain effect of enriched skim milk powder on reducing gout flares and the other found no benefit of vitamin C on serum uric acid reduction.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

2.

Dietary supplement interactions with antiretrovirals: a systematic review.

Author: JallohMohamed A, GregoryPhilip J, HeinDarren, Risoldi CochraneZara, RodriguezAleah

HIV treatment
Drug-supplement interactions

This systematic review investigated interactions between dietary supplements and antiretrovirals, identifying several supplements that can significantly affect antiretroviral levels.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

3.

Dietary supplements for chronic gout.

Author: AndrésMariano, SiveraFrancisca, BuchbinderRachelle, Pardo PardoJordi, CarmonaLoreto

Pain reduction
Gastrointestinal events
Study withdrawal

There was no high-quality evidence to support or refute the use of glycomacropeptide-enriched skim milk powder or vitamin C for adults with chronic gout.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

4.

Assessment of Physicochemical Parameters and Contaminants in Herbal Dietary Supplements Used in the Treatment of Inflammatory Bowel Disease.

Author: Amidžić KlarićDaniela, KovačićJelena, JeličićMario-Livio, ZubčićSnježana, StankovVladimir, Gulan ČičakMarija, BučarBoris, KlarićIlija, MornarAna

Ethylene oxide contamination
Gluten contamination

Herbal supplements for inflammatory bowel disease (IBD) were assessed for quality and safety. Most met USP requirements but some contained high levels of gluten or ethylene oxide, highlighting the need for strict quality control.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

5.

Probiotics and Prebiotics as Dietary Supplements for the Adjunctive Treatment of Type 2 Diabetes.

Author: WangYuying, WenLina, TangHuazhen, QuJinxiu, RaoBenqiang

Improved gut health
Reduced insulin resistance

Probiotics and prebiotics may help improve dysbiosis and gut-related inflammation in type 2 diabetes (T2D) patients, potentially reducing insulin resistance and lowering blood glucose.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

6.

Rosmarinic Acid and Related Dietary Supplements: Potential Applications in the Prevention and Treatment of Cancer.

Author: ZhaoJiachao, XuLiwei, JinDi, XinYu, TianLin, WangTan, ZhaoDaqing, WangZeyu, WangJing

Cancer prevention

This review highlights the anti-tumor potential of rosmarinic acid (RA), a natural compound with excellent antioxidant properties. The review discusses the use of RA-enriched dietary supplements for cancer prevention and treatment, as well as techniques to improve its bioavailability. RA demonstrates anticancer activity by regulating oxidative stress, chronic inflammation, cell cycle, apoptosis, and metastasis, suggesting its potential for use in anti-tumor drug development.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

8.

Dietary supplements for treatment of endometriosis: A review.

Author: Yalçın BahatPınar, AyhanIşıl, Üreyen ÖzdemirEda, İncebozÜmit, OralEngin

Endometriosis treatment

This review evaluated the potential of dietary supplements as a complementary treatment for endometriosis. The review examined the effects of various supplements, including vitamin D, zinc, magnesium, omega 3, and others, on endometriosis symptoms and progression.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

12.

Comparison of Two Dietary Supplements for Treatment of Uric Acid Renal Lithiasis: Citrate vs. Citrate + Theobromine.

Author: HernandezYumaira, Costa-BauzaAntonia, CalvóPaula, BenejamJoan, SanchisPilar, GrasesFelix

UA lithiasis treatment

Uric acid renal lithiasis, a condition characterized by the formation of kidney stones, has a high rate of recurrence. While alkalization with citrate is a common treatment, theobromine, a compound found in chocolate and cocoa, shows promise as a potent inhibitor of uric acid crystallization.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

14.

Diet and eczema: a review of dietary supplements for the treatment of atopic dermatitis.

Author: SchlichteMegan J, VandersallAbbey, KattaRajani

Prebiotics for AD
Probiotics for AD
No dietary supplements recommended

There is no evidence to support the use of dietary supplements for the treatment of atopic dermatitis. Probiotics and prebiotics may be effective, but more research is needed to determine the optimal dose and strains.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

15.

Third-Party Evaluation: A Review of Dietary Supplements Dispensed by Military Treatment Facilities From 2007 to 2011.

Author: JonesDonnamaria R, KasperKorey B, DeusterPatricia A

The study highlighted the importance of third-party certification/verification for ensuring high-quality dietary supplements (DS). This is crucial for physicians who may prescribe DS to patients.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.