Zolmitriptan inhibits neurogenic inflammation and pain during electrical stimulation in human skin.

Author: BestC, BirkleinF, DöringK, KrämerH H

Paper Details 
Original Abstract of the Article :
BACKGROUND: Triptans are agonists to 5-HT 1B/D/F receptors, which are present on nociceptive neurons not only within but also beyond the trigeminal system. The aim of this study was to investigate whether zolmitriptan interacts with peptidergic nociceptive afferents in human skin. METHODS: Twenty p...See full text at original site
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引用元:
https://doi.org/10.1002/ejp.622

データ提供:米国国立医学図書館(NLM)

Zolmitriptan: Taming the Inflammatory Storm in Human Skin

Pain, a harsh reality of life, can often be traced to the intricate communication network of nerves in our bodies. When this network malfunctions, it can lead to inflammation and pain. This study explores the potential of zolmitriptan, a medication typically used to treat migraines, to target this communication network and alleviate pain in the skin.

The researchers, like explorers venturing into a previously uncharted territory, investigated the effects of zolmitriptan on electrically induced neurogenic flare and pain in human skin. Their findings, like a cool oasis in the heat of pain, revealed that zolmitriptan significantly reduced both the flare response and the perceived pain. This suggests that zolmitriptan may offer a novel approach to managing pain and inflammation in the skin.

A Cool Oasis in the Heat of Pain: Zolmitriptan for Skin Inflammation

This study suggests that zolmitriptan may offer a new avenue for managing pain and inflammation in the skin. The researchers’ findings highlight the potential of targeting the nerve communication network to alleviate pain. This could be a valuable tool for treating a range of skin conditions associated with inflammation and pain.

Navigating the Desert of Pain: Finding Relief in the Skin

This research offers a glimmer of hope for those suffering from skin pain and inflammation. The researchers’ findings suggest that zolmitriptan may provide a unique and effective way to manage these conditions. It could offer a cool oasis of relief in the desert of pain.

Dr.Camel's Conclusion

This study suggests that zolmitriptan may offer a new and effective way to manage pain and inflammation in the skin. The researchers’ findings provide a fascinating glimpse into the potential of targeting the nerve communication network to alleviate pain. This research could lead to new and innovative treatments for skin conditions.

Date :
  1. Date Completed 2016-08-15
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25395191

DOI: Digital Object Identifier

10.1002/ejp.622

Related Literature

SNS
PICO Info
in preparation
Languages

English

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