Vanishing bile duct syndrome in the context of concurrent temozolomide for glioblastoma.

Author: AdeyiOyedele, FungScott, MasonMatthew, MillarBarbara-Ann

Paper Details 
Original Abstract of the Article :
Temozolomide, an oral alkylating agent, is used in the treatment of glioblastoma. We describe a case of a 62-year-old woman developing jaundice with significant derangement of liver function tests on day 17 of focal radiotherapy with concomitant temozolomide. There was no structural abnormality on i...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248108/

データ提供:米国国立医学図書館(NLM)

Vanishing Bile Duct Syndrome: A Rare Desert Storm

The human body is a complex desert, with intricate systems working together to maintain health. This study, like a skilled desert guide, investigates a rare and perplexing condition known as vanishing bile duct syndrome. The researchers, like careful observers of the desert landscape, chronicle the case of a patient who developed jaundice, a yellowing of the skin and eyes, after receiving temozolomide, a chemotherapy drug used to treat glioblastoma, a type of brain cancer. The study highlights the potential for temozolomide to trigger this unusual syndrome, emphasizing the importance of vigilance and timely intervention in managing the condition.

A Rare Desert Storm: Unmasking Vanishing Bile Duct Syndrome

This study, like a rare desert bloom, sheds light on a little-known condition, vanishing bile duct syndrome. The researchers, like skilled botanists, carefully document the case, highlighting the potential link between temozolomide and this unusual syndrome. This discovery is a valuable contribution to the understanding of this rare and potentially serious condition, emphasizing the need for continued research to uncover its causes and develop effective treatments.

Navigating the Desert of Liver Health

The desert of liver health is vast and intricate, with many potential hazards. This study, like a cautionary tale, reminds us of the importance of careful monitoring and timely intervention when managing patients undergoing chemotherapy. Vanishing bile duct syndrome, like a rare and unexpected sandstorm, can pose significant challenges, but with prompt diagnosis and appropriate treatment, patients can navigate these treacherous waters with greater success.

Dr. Camel's Conclusion

This research, like a fleeting glimpse of a rare desert phenomenon, highlights the importance of vigilance and careful observation in managing patients undergoing chemotherapy. The case of vanishing bile duct syndrome underscores the need for continued research into the potential side effects of medications, especially in the complex landscape of cancer treatment.

Date :
  1. Date Completed 2015-07-23
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25432915

DOI: Digital Object Identifier

PMC4248108

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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