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Anatomy, physiology and neurobiology of the nociception: a focus on low back pain (part A).

Author: BlondS, DavidR, MertensP, RigoardP

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Treating Failed Back Surgery Syndrome (FBSS) is challenging due to the complex combination of lingering pain from surgery and changes in the nervous system that lead to chronic pain. This paper examines the pathways involved in pain sensation, aiming to understand the physical aspects of back pain.
Paper Details　
Original Abstract of the Article :
The treatment of Failed Back Surgery Syndrome (FBSS) remains a challenge for pain medicine due to the complexity in the interactions between [1] a residual mechanical pain after surgery and, [2] a progressive transition into chronic pain involving central nervous system plasticity and molecular reor...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.neuchi.2014.09.001

データ提供：米国国立医学図書館（NLM）

Decoding the Complexities of Low Back Pain

This study delves into the intricate world of nociception, the process by which pain signals are transmitted through the nervous system. The authors focus on the specific challenge of low back pain, particularly in the context of Failed Back Surgery Syndrome (FBSS). This research sheds light on the underlying mechanisms involved in low back pain and provides a framework for understanding the transition from acute to chronic pain.

Understanding the Pain Pathway

The authors provide a comprehensive overview of the pain pathway, highlighting the key players involved in the perception of pain. They emphasize the complex interplay between mechanical pain, arising from residual surgical damage, and central nervous system plasticity, which contributes to the development of chronic pain. This research underscores the importance of understanding the intricate mechanisms involved in pain perception and the role of central nervous system adaptations in chronic pain conditions.

Navigating the Desert of Chronic Pain

Chronic pain conditions, like FBSS, can be a challenging desert to navigate. This research offers a valuable guidepost, shedding light on the underlying mechanisms driving chronic pain. By understanding these mechanisms, we can develop more effective strategies for treating chronic pain and improving the quality of life for those affected by these conditions.

Dr.Camel's Conclusion

Navigating the desert of chronic pain can be a long and arduous journey. This research offers a valuable map, highlighting the complex interplay between mechanical pain and central nervous system adaptations. By understanding these mechanisms, we can develop more effective strategies for treating chronic pain and improving the lives of those affected by these conditions.

Date :
  1. Date Completed 2015-11-25
  2. Date Revised 2016-04-14
Further Info :

Pubmed ID

25441598

DOI: Digital Object Identifier

10.1016/j.neuchi.2014.09.001

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PICO Info
in preparation
Languages

English

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