mTOR inhibitor-associated stomatitis (mIAS) in three patients with cancer treated with everolimus.

Author: KalogirouEleni-Marina, PiperiEvangelia P, SklavounouAlexandra, TosiosKonstantinos I

Paper Details 
Original Abstract of the Article :
Mammalian targets of rapamycin inhibitors (mTOR inhibitors, mTORI) are indicated for the management of several cancer types, including hormone receptor--positive or HER2-negative breast cancer, advanced renal cell carcinoma, advanced neuroendocrine tumors of pancreatic origin, and tuberous sclerosis...See full text at original site
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引用元:
https://doi.org/10.1016/j.oooo.2014.08.023

データ提供:米国国立医学図書館(NLM)

mTOR Inhibitor-Associated Stomatitis (mIAS): A Case Study

Mammalian target of rapamycin inhibitors (mTOR inhibitors) are powerful drugs used to treat various cancers. However, one of the common side effects associated with these drugs is mTOR inhibitor-associated stomatitis (mIAS), characterized by painful ulcers in the mouth. This study describes the clinical presentation and management of mIAS in three patients receiving everolimus, an mTOR inhibitor.

mIAS: A Desert of Discomfort

The study highlights the common symptoms of mIAS and how these ulcers typically manifest in patients receiving mTOR inhibitors. The researchers found that a “magic mouthwash” solution containing dexamethasone, lidocaine, doxycycline, and sucralfate proved effective in alleviating symptoms and promoting healing.

Navigating the Desert of Side Effects

Just as a camel needs to find a way to quench its thirst in the desert, patients receiving mTOR inhibitors need effective strategies to manage side effects. This study provides valuable insights into the treatment of mIAS, a common and often uncomfortable side effect of mTOR inhibitors. Always consult with your healthcare provider to discuss potential side effects and develop a plan to manage them.

Dr.Camel's Conclusion

This case study highlights the importance of recognizing and managing mIAS, a common side effect of mTOR inhibitors. The use of a “magic mouthwash” solution appears to be an effective strategy for relieving symptoms and promoting healing. Remember, open communication with your healthcare provider is crucial for managing any side effects you may experience while on medication.

Date :
  1. Date Completed 2015-07-14
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

25442249

DOI: Digital Object Identifier

10.1016/j.oooo.2014.08.023

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SNS
PICO Info
in preparation
Languages

English

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