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mTOR inhibitor-associated stomatitis (mIAS) in three patients with cancer treated with everolimus.
Author: KalogirouEleni-Marina, PiperiEvangelia P, SklavounouAlexandra, TosiosKonstantinos I
Original Abstract of the Article :
Mammalian targets of rapamycin inhibitors (mTOR inhibitors, mTORI) are indicated for the management of several cancer types, including hormone receptor--positive or HER2-negative breast cancer, advanced renal cell carcinoma, advanced neuroendocrine tumors of pancreatic origin, and tuberous sclerosis...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.oooo.2014.08.023
データ提供:米国国立医学図書館(NLM)
mTOR Inhibitor-Associated Stomatitis (mIAS): A Case Study
Mammalian target of rapamycin inhibitors (mTOR inhibitors) are powerful drugs used to treat various cancers. However, one of the common side effects associated with these drugs is mTOR inhibitor-associated stomatitis (mIAS), characterized by painful ulcers in the mouth. This study describes the clinical presentation and management of mIAS in three patients receiving everolimus, an mTOR inhibitor.
mIAS: A Desert of Discomfort
The study highlights the common symptoms of mIAS and how these ulcers typically manifest in patients receiving mTOR inhibitors. The researchers found that a “magic mouthwash” solution containing dexamethasone, lidocaine, doxycycline, and sucralfate proved effective in alleviating symptoms and promoting healing.
Navigating the Desert of Side Effects
Just as a camel needs to find a way to quench its thirst in the desert, patients receiving mTOR inhibitors need effective strategies to manage side effects. This study provides valuable insights into the treatment of mIAS, a common and often uncomfortable side effect of mTOR inhibitors. Always consult with your healthcare provider to discuss potential side effects and develop a plan to manage them.
Dr.Camel's Conclusion
This case study highlights the importance of recognizing and managing mIAS, a common side effect of mTOR inhibitors. The use of a “magic mouthwash” solution appears to be an effective strategy for relieving symptoms and promoting healing. Remember, open communication with your healthcare provider is crucial for managing any side effects you may experience while on medication.
Date :
- Date Completed 2015-07-14
- Date Revised 2015-11-19
Further Info :
Related Literature
English
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