Side Effects of sucralfate: A Synthesis of Findings from 31 Studies

  1. Home
  2. Side Effects of sucralfate
This information is not medical advice and is not a substitute for diagnosis or treatment by a physician.Data sources and disclaimers (data limitations, copyright, etc.)The analysis on "Side Effects of sucralfate: A Synthesis of Findings from 31 Studies" on this page is based on PubMed data provided by the U.S. National Library of Medicine (NLM). However, NLM does not endorse or verify these analyses.

This analysis is based on research papers included in PubMed, but medical research is constantly evolving and may not fully reflect the latest findings. There may also be biases towards certain research areas.

This information is not medical advice and is not a substitute for diagnosis or treatment by a physician. If you have concerns about "Side Effects of sucralfate: A Synthesis of Findings from 31 Studies", please consult your doctor.

For NLM copyright information, please see Link to NLM Copyright Page
PubMed data is obtained via Hugging Face Datasets: Link to DatasetPlease check the disclaimer.
This page's analysis is based on PubMed data provided by the U.S. National Library of Medicine (NLM).
Original Abstract of the Article

Main Research Findings

Sucralfate is a medication used to treat ulcers in the stomach and intestines. Studies have shown that sucralfate is effective in treating gastric ulcers. 29 , 20 Sucralfate has also been shown to be helpful in treating and preventing mouth sores caused by chemotherapy. 11 , 30 It has also been shown to be effective in preventing skin irritation caused by radiation therapy. 24 , 8

Reasons for Side Effects

Sucralfate side effects can be caused by the drug staying in the stomach. 14 Sucralfate reacts with stomach acid to form a thick gel. This gel can remain in the stomach and lead to side effects such as indigestion and constipation.

Common Side Effects

Constipation

Sucralfate can cause constipation because it forms a gel in the stomach. 14 Constipation has been reported in about 10% of patients taking sucralfate. 5 If you experience severe constipation, consult your doctor.

Indigestion

Sucralfate can cause indigestion when it remains in the stomach. 14 Indigestion has been reported in about 5% of patients taking sucralfate. 5 If you experience severe indigestion, consult your doctor.

Fullness

Sucralfate can cause fullness when it remains in the stomach. 14 If you experience severe fullness, consult your doctor.

Nausea

Sucralfate can cause nausea. 5 If you experience severe nausea, consult your doctor.

Tinnitus

Sucralfate can cause tinnitus. 3 If you experience severe tinnitus, consult your doctor.

Other Side Effects

Other side effects of sucralfate have been reported, including dry mouth, taste changes, rash, and itching. 2 If you experience any of these symptoms, consult your doctor.

Countermeasures for Side Effects

Constipation

To prevent constipation, it is important to eat a diet high in fiber and drink plenty of fluids. Light exercise can also be helpful. 14 If constipation does not improve, consult your doctor.

Indigestion

To prevent indigestion, it is important to eat small meals and eat slowly. It is also important to eat digestible foods and avoid fatty or spicy foods. 14 If indigestion does not improve, consult your doctor.

Fullness

To prevent fullness, it is important to eat small meals and eat slowly. Also, avoid lying down after meals and try to do some light exercise. 14 If fullness does not improve, consult your doctor.

Nausea

To prevent nausea, it is important to stay hydrated. Taking anti-nausea medication can also be effective. 5 If you experience severe nausea, consult your doctor.

Tinnitus

To prevent tinnitus, it is important to stop taking sucralfate. 3 If you experience severe tinnitus, consult your doctor.

Comparison between Studies

Commonalities of Studies

Many studies have shown that sucralfate is effective in treating gastric ulcers and peptic ulcers. 29 , 20 Sucralfate has also been shown to be effective in preventing and treating chemotherapy-induced stomatitis. 11 , 30 Furthermore, sucralfate has been shown to be effective in preventing radiation therapy-induced skin inflammation. 24 , 8

Differences between Studies

Different studies have reported different results regarding sucralfate side effects. For example, constipation has been reported in about 10% of patients taking sucralfate, 5 but other studies have reported lower rates of constipation. Further research on sucralfate side effects is needed.

Precautions for Application in Daily Life

Sucralfate is effective in treating gastric ulcers and peptic ulcers, but it can cause side effects. When taking sucralfate, follow your doctor's instructions carefully and consult your doctor immediately if you experience any side effects.

Limitations of Current Research

The side effects of sucralfate are not yet fully understood. Further research is needed to study the side effects of sucralfate in more detail.

Future Directions for Research

To study the side effects of sucralfate in more detail, it is necessary to conduct research on the long-term effects of sucralfate. It is also necessary to research methods to reduce the side effects of sucralfate.

Conclusion

Sucralfate is an effective drug for the treatment of gastric ulcers and peptic ulcers, but it can cause side effects. When taking sucralfate, follow your doctor's instructions carefully and consult your doctor immediately if you experience any side effects. The side effects of sucralfate are not yet fully understood. Further research is needed to study the side effects of sucralfate in more detail.

Keywords
Benefit Keywords
Reduces hyperphosphatemia
2
Improved patient safety
Ototoxic drug identification
3
Hyperphosphatemia control
5
Management of cancer
6
Pain relief
Post-tonsillectomy recovery
7
Reduced skin damage
8
Reduced radio-epithelitis
9
Resolves nonregenerative anemia
10
EB treatment
12
Gastrointestinal protection
Mucosal healing
13
Posttonsillectomy pain reduction
15
Ulcer healing
17
Reduced side effects
18
Duodenal ulcer treatment
Sucralfate effective
20
High healing rate
No biochemical effects
Well tolerated
21
Vaginal ulceration treatment
22
Eradicate H. pylori
23
Faster skin recovery
Prevents skin reaction
24
Effective prevention
Increased knowledge
Reduced respiratory complications
Sucralfate effective
25
Analgesic
Anti-inflammatory
Antithrombotic
26
NSAID-induced ulcer prevention
28
Gastric ulcer healing
29
Reduced chemotherapy-induced symptoms
Well tolerated
30
Heterotopic ossification prevention
31
Risk Keywords
Intestinal necrosis
1
Aluminium toxicity
2
Hearing loss risk
Ototoxic drug reactions
3
Drug-induced esophagitis
Esophageal ulcers
4
Lack of efficacy
Side effects
5
mTORI-associated stomatitis
6
No side effects reported
7
Potential complications
8
Production of antibodies
10
No significant advantage over placebo
11
Abdominal distension
Acute occlusion
Bezoar formation
Nasogastric tube bezoar
14
Esophageal bezoar
16
NSAID-induced gastropathy
17
Rare side effects
21
None mentioned
23
Rare side effects
24
Cost
Microbial resistance
Serious consequences
Uncontrolled practice factors
25
Esophagitis
Gastrointestinal bleeding
Peptic ulcer
26
Dyspepsia
Hemorrhage
Perforation
Ulcers
27
No difference in side effects
29
Gastrointestinal side-effects
31
Literature analysis of 31 papers
Positive Content
21
Neutral Content
3
Negative Content
7
Article Type
7
1
1
10
31
1.

Risk of Intestinal Necrosis With Sodium Polystyrene Sulfonate: A Systematic Review and Meta-analysis.

Author: HolleckJürgen L, RobertsAndrea E, MarhofferElizabeth A, GrimshawAlyssa A, GundersonCraig G

Intestinal necrosis

This systematic review examines the gastrointestinal side effects of sodium polystyrene sulfonate (SPS), particularly intestinal necrosis. The review included studies with controls and reported the rates of intestinal necrosis associated with SPS.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

2.

Sucralfate--safety and side effects.

Author: MarksI N

Reduces hyperphosphatemia
Aluminium toxicity

Sucralfate is generally safe, with minimal aluminium absorption and ready renal excretion. Potential drug interactions with phenytoin, fluoroquinolone antibiotics, and H2-receptor blockers should be considered.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

4.

L-arginine-induced esophagitis, report of six cases.

Author: ParraPedro Rivero-Borrell de la, González-CruzMiguel Á, Ferreiro-MarinAlejandro, Casaubón-GarcínPablo R

Drug-induced esophagitis
Esophageal ulcers

This case report found that L-arginine can cause esophagitis in adolescents. The report suggests that drug-induced esophagitis should be considered as a possible diagnosis in adolescents with acute severe odynophagia, dysphagia, and retrosternal pain.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

5.

Evaluating Sucralfate as a Phosphate Binder in Normal Cats and Cats with Chronic Kidney Disease.

Author: QuimbyJessica, LappinMichael

Hyperphosphatemia control
Lack of efficacy
Side effects

Sucralfate is investigated as a phosphate binder for hyperphosphatemia in CKD cats. While sucralfate did not show significant efficacy, it caused side effects such as vomiting and decompensation in some cats.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

6.

mTOR inhibitor-associated stomatitis (mIAS) in three patients with cancer treated with everolimus.

Author: KalogirouEleni-Marina, TosiosKonstantinos I, PiperiEvangelia P, SklavounouAlexandra

Management of cancer
mTORI-associated stomatitis

mTOR inhibitors like everolimus can cause mTORI-associated stomatitis, characterized by oral ulcers, which can be effectively managed with a magic mouthwash solution.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

7.

Efficacy of sucralfate for the treatment of post-tonsillectomy symptoms.

Author: SiupsinskieneNora, ŽekonienėJurgita, PadervinskisEvaldas, ŽekonisGediminas, VaitkusSaulius

Pain relief
Post-tonsillectomy recovery
No side effects reported

Tonsillectomy is a common surgery that can cause significant post-operative pain. This study investigated the use of topical sucralfate, a medication that helps protect the stomach lining, to reduce pain after tonsillectomy. The results showed that sucralfate effectively reduced pain and improved recovery time.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

8.

The use of antioxidants in radiotherapy-induced skin toxicity.

Author: AmberKyle T, ShimanMichael I, BadiavasEvangelos V

Reduced skin damage
Potential complications

This review summarizes the use of antioxidants in preventing or treating radiation-induced skin damage. Several antioxidants are discussed, including their role as free radical scavengers, and the possible complications of using such therapy.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

9.

[Importance of local skin treatments during radiotherapy for prevention and treatment of radio-induced epithelitis].

Author: ChargariC, FromantinI, KirovaY M

Reduced radio-epithelitis

This review of literature focuses on treatments for radio-epithelitis, a common problem in radiation therapy. Despite preclinical rationale, aloe vera and trolamine have not shown benefit in preventing radio-epithelitis. Calendula Officinalis was found to be superior to trolamine for preventing radio-epithelitis, while hyaluronic acid and silver leaf show promising results in reducing the intensity of cutaneous radio-induced side effects. Further trials are needed to determine evidence-based treatments.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : French

10.

Use of human recombinant erythropoietin for the treatment of nonregenerative anemia in a rough-toothed dolphin (Steno bredanensis).

Author: ManireC A, RhinehartH L

Resolves nonregenerative anemia
Production of antibodies

Human recombinant erythropoietin was found to be effective in treating nonregenerative anemia in a rough-toothed dolphin. However, long-term use may lead to the production of antibodies to erythropoietin, which could cause serious side effects.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

11.

Sucralfate in the treatment of chemotherapy-induced stomatitis: a double-blind, placebo-controlled pilot study.

Author: ChiaraS, NobileM T, VincentiM, GozzaA, PastroneI, RossoM, RossoR

No significant advantage over placebo

Sucralfate gel did not demonstrate a significant advantage over placebo in the treatment of chemotherapy-induced mucositis. In a pilot study of 40 patients, both groups had similar objective response rates and pain scores.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

13.

Role of sucralfate in gastrointestinal diseases.

Author: CandelliM, CarloniE, ArmuzziA, CammarotaG, OjettiV, PignataroG, SantoliquidoA, PolaR, PolaE, GasbarriniG, GasbarriniA

Gastrointestinal protection
Mucosal healing

This paper describes the current and potential future uses of sucralfate in the management of gastrointestinal disorders. Sucralfate is a cytoprotective drug widely used for gastro-esophageal reflux, gastritis, peptic ulcer, and other GI diseases.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

14.

[Sucralfate and bezoars: data from the system of pharmacologic vigilance and review of the literature].

Author: GuyC, OllagnierM

Abdominal distension
Acute occlusion
Bezoar formation
Nasogastric tube bezoar

Sucralfate is used to treat peptic ulcers. However, it can form bezoars in the gut, especially in critically ill patients, newborns, and those receiving nasogastric tube feeding. This study suggests that caution should be exercised when using sucralfate in these populations.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : French

15.

Sucralfate for posttonsillectomy analgesia.

Author: OzcanM, AltuntaşA, UnalA, NalçaY, AslanA

Posttonsillectomy pain reduction

This controlled study investigated the effectiveness of sucralfate in reducing post-tonsillectomy pain in 80 patients. The results showed that sucralfate significantly reduced throat pain and analgesic requirements after surgery.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

16.

[Esophageal bezoar in a child treated with sucralfate].

Author: RazafimahefaH, MouterdeO, DevauxA M

Esophageal bezoar

A 11-year-old girl with severe encephalitis complicated by seizures developed an esophageal bezoar after receiving sucralfate, a morphinic compound, phenobarbital, curare, and enteral feeding. This case highlights the importance of caution when combining enteral feeding and sucralfate in patients with risk factors such as plurimedication, dehydration, and impaired gastric motility.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : French

17.

Therapy of NSAIDs-induced gastropathy.

Author: La CorteR, CaselliM, RuinaM, BajocchiG, AlvisiV, TrottaF

Ulcer healing
NSAID-induced gastropathy

Omeprazole is the most efficient drug for NSAID-gastropathy, while H2 blockers, sucralfate, and misoprostol are less effective.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

18.

Daily-diary evaluated side-effects of conformal versus conventional prostatic cancer radiotherapy technique.

Author: WidmarkA, FranssonP, FranzénL, LittbrandB, HenrikssonR

Reduced side effects

Conformal radiotherapy for prostate cancer is associated with fewer side effects compared to conventional radiotherapy. Sucralfate may reduce intestinal morbidity in patients undergoing conformal radiotherapy.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

19.

Efficacy of sucralfate in treatment of non-ulcer dyspepsia. A double-blind placebo-controlled study.

Author: GudjónssonH, OddssonE, BjörnssonS, GunnlaugssonO, TheodorsA, JónassonT A, BonnevieO, ThjodleifssonB

Sucralfate did not demonstrate symptomatic improvement over placebo in the treatment of non-ulcer dyspepsia (NUD). Both sucralfate and placebo groups showed similar improvements in symptoms.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

21.

[Therapy of ulcer disease using gastrinal-sucralfate produced in Czechoslovakia].

Author: MünzováH, HusováL, KunovskáM, HepA, DítĕP, ZborilV, ZábranskáS

High healing rate
No biochemical effects
Well tolerated
Rare side effects

Gastrinal-Sucralphate is highly effective in treating gastroduodenal ulceration, with better tolerance observed with the granulate form.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Czech

22.

Topical sucralfate in the treatment of vaginal ulceration.

Author: LentzS S, BarrettR J, HomesleyH D

Vaginal ulceration treatment

Sucralfate vaginal douches were successful in treating three cases of vaginal ulceration after traditional methods of treatment had failed. The treatment was well tolerated and had no side effects.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

23.

Short report: evaluation of Helicobacter pylori eradication with bismuth sucralfate.

Author: ReijersM H, NoachL A, TytgatG N

Eradicate H. pylori
None mentioned

This pilot study evaluated the efficacy of bismuth sucralfate in eradicating H. pylori infection in 10 patients with chronic dyspepsia.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

24.

Skin protection by sucralfate cream during electron beam therapy.

Author: MaicheA, IsokangasO P, GröhnP

Faster skin recovery
Prevents skin reaction
Rare side effects

Sucralfate cream significantly prevented and accelerated the recovery of acute radiation reaction of the skin in breast cancer patients receiving postoperative electron beam therapy, compared to a base cream.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

26.

Nonsteroidal antiinflammatory drugs and the gastrointestinal tract.

Author: HirschowitzB I

Analgesic
Anti-inflammatory
Antithrombotic
Esophagitis
Gastrointestinal bleeding
Peptic ulcer

This study discussed the risks and benefits of nonsteroidal antiinflammatory drugs (NSAIDs), particularly the potential for gastrointestinal side effects. The authors emphasized the importance of rational use and the need for effective preventive and treatment strategies.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

27.

[Ulcer prevention during anti-rheumatism therapy and in intensive medicine].

Author: KoelzH R

Dyspepsia
Hemorrhage
Perforation
Ulcers

This article discusses gastrointestinal side effects of nonsteroidal anti-inflammatory drugs (NSAIDs) and strategies for prevention. Prophylactic antiulcer treatment is recommended in high-risk patients.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : German

28.

Prevention of nonsteroidal anti-inflammatory drug-induced gastroduodenal ulcers: role of mucosal protective and gastric antisecretory drugs.

Author: DajaniE Z, AgrawalN M

NSAID-induced ulcer prevention

Misoprostol is more effective than other antiulcer drugs in preventing NSAID-induced gastric and duodenal ulcers in patients receiving chronic NSAID therapy.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

29.

Sucralfate and ranitidine twice daily in the treatment of gastric ulcer. A multicenter randomized double-blind study.

Author: ArchimandritisA, CharitopoulosN, DiamantisT, KitisG, KokozidisG, MallasE, TjivrasM

Gastric ulcer healing
No difference in side effects

Sucralfate and ranitidine were equally effective in the short-term treatment of gastric ulcers. Both drugs achieved similar healing rates at 4 and 8 weeks.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

31.

[Prevention of ossification after total hip endoprosthesis with indomethacin and its effect on gastric mucosa].

Author: MetzenrothH, PubligW, KnahrK, ZandlC, KuchnerG, CardaC

Heterotopic ossification prevention
Gastrointestinal side-effects

Ranitidine and sucralfate were both found to effectively prevent ulcers in patients receiving indomethacin as a prophylactic against heterotopic ossification after total hip joint replacement. The study included 3 groups: ranitidine, sucralfate, and placebo. Both ranitidine and sucralfate were effective in preventing ulcers, and indomethacin was effective in preventing heterotopic ossification.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : German

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.