Paper Details

  1. Home
  2. Paper Details

Efficacy of strontium ranelate in combination with a D-hormone analog for the treatment of postmenopausal osteoporosis.

Author: AbboskhujaevaLola S, AlikhanovaNodira M, IsmailovSaydiganikhodja I

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Strontium ranelate and alfacalcidol combination therapy improved bone quality, fall risk, and markers of bone turnover to a greater extent than strontium ranelate alone in patients with established osteoporosis.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Vitamin D supplements are recommended in individuals with vitamin D insufficiency and established osteoporosis to reduce risk of fracture and falling. Active vitamin D metabolites have been found to be more effective for fall prevention than native vitamin D. OBJECTIVES: The aim of this...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269821/

データ提供：米国国立医学図書館（NLM）

Strontium Ranelate and Alfacalcidol: A Powerful Combination for Osteoporosis Treatment

This [clinical trial] investigates the [efficacy of strontium ranelate] in [combination with alfacalcidol] for the [treatment of postmenopausal osteoporosis]. The authors compared the [effects of strontium ranelate monotherapy] and [strontium ranelate plus alfacalcidol] on [bone mineral density (BMD), fall risk, and markers of bone turnover] in [postmenopausal women]. The study found that [strontium ranelate combination therapy] resulted in [significantly greater improvements] in [BMD, fall risk, and bone turnover] compared to [strontium ranelate alone]. These findings suggest that [combination therapy] may be [a more effective approach] for [treating postmenopausal osteoporosis] and [reducing fracture risk].

Optimizing Osteoporosis Treatment

The study found that [strontium ranelate combination therapy] [significantly improved] [BMD] at [the lumbar spine and proximal femora], indicating [increased bone density]. This [positive impact] on [bone health] may [reduce the risk of fractures] in [postmenopausal women].

Protecting Against Fractures and Falls

The research highlights the [importance of considering] [combination therapy] for [postmenopausal osteoporosis]. By [combining strontium ranelate with alfacalcidol], we can [optimize bone health] and [reduce the risk of fractures and falls] in [women with osteoporosis].

Dr.Camel's Conclusion

Like a camel's strong bones that allow it to navigate harsh desert terrain, maintaining healthy bones is crucial for overall well-being. This study demonstrates the [effectiveness of combining strontium ranelate with alfacalcidol] in [strengthening bones] and [reducing fracture risk] in [women with osteoporosis].

Date :
  1. Date Completed 2016-02-22
  2. Date Revised 2023-11-11
Further Info :

Pubmed ID

25480348

DOI: Digital Object Identifier

PMC4269821

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.