Four-times-a-day dosing frequency is better than a twice-a-day regimen in subjects requiring a high-dose inhaled steroid, budesonide, to control moderate to severe asthma.

Author: BurekA, CartierA, GhezzoH, JenningsB H, MaloJ L, MerlandN, MorrisJ

Paper Details 
Original Abstract of the Article :
Fifty-three adult asthmatic subjects requiring 800 micrograms or more of inhaled beclomethasone dipropionate were enrolled in a double-blind parallel group study of 6-month duration to compare the efficacy and side effects of inhaled budesonide in doses of 800, 1,200, and 1,600 micrograms given two ...See full text at original site
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引用元:
https://doi.org/10.1164/ajrccm/140.3.624

データ提供:米国国立医学図書館(NLM)

Four-times-a-day dosing frequency is better than a twice-a-day regimen in subjects requiring a high-dose inhaled steroid, budesonide, to control moderate to severe asthma

Asthma, like a desert windstorm, can make breathing a challenge. This study, published in 1991, explores the effectiveness of different dosing regimens for budesonide, an inhaled steroid used to manage asthma. The researchers wanted to determine if taking the medication four times a day was more effective than taking it twice a day for patients with moderate to severe asthma.

More Frequent Dosing - Finding the Right Rhythm

The study found that patients who took budesonide four times a day experienced fewer asthma symptoms and fewer relapses compared to those who took it twice a day. It's like realizing that a camel needs to drink water more frequently during a scorching desert journey. The researchers suggest that more frequent dosing might help maintain a more consistent level of medication in the body, improving its effectiveness.

Managing Asthma - Finding the Right Balance

This research highlights the importance of finding the right dosing regimen for managing asthma. It's a reminder that, just as a camel needs to adapt its pace and water intake to the changing conditions of the desert, we need to tailor treatment plans to the individual needs of each patient. This study encourages us to be proactive in managing asthma, working with our healthcare providers to find the best approach for our individual needs.

Dr.Camel's Conclusion

This research is a valuable reminder that even seemingly minor adjustments, like changing the frequency of medication, can have a significant impact on the effectiveness of treatment. It underscores the importance of personalized medicine and working closely with healthcare providers to find the best approach for managing chronic conditions. It's like finding the right rhythm for a long desert trek, ensuring a smoother and more successful journey.

Date :
  1. Date Completed 1989-10-19
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

2551204

DOI: Digital Object Identifier

10.1164/ajrccm/140.3.624

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