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The role of biological agents in the management of large vessel vasculitis (LVV): a systematic review and meta-analysis.

Author: DrydenDonna M, OsmanMohammed, PagnouxChristian, StorieDale, YacyshynElaine

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Biological agents, like anti-TNF agents, were not effective for remission or reduction of corticosteroid use in patients with giant cell arteritis (GCA). However, tocilizumab and infliximab may be effective for GCA and refractory Takayasu's arteritis (TAA), respectively, although more research is needed.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Giant cell arteritis (GCA) and Takayasu's arteritis (TAA) are large vessel vasculitides (LVV) for which corticosteroids (CS) are the mainstay for treatment. In patients with LVV unable to tolerate CS, biological agents have been used with variable effectiveness. OBJECTIVE: To systematic...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269410/

データ提供：米国国立医学図書館（NLM）

The role of biological agents in the management of large vessel vasculitis (LVV): a systematic review and meta-analysis.

This study, conducted in the field of [研究分野], explores the effectiveness of [研究手法] for treating [研究手法]. The authors performed a comprehensive review of existing research to [主な目的] and assess the safety and efficacy of these treatments. They found that [主要な発見] , highlighting the need for more robust clinical trials to clarify the role of biological agents in this complex condition. This research is like a map of the vast desert of vasculitis, guiding us towards more effective treatment strategies.

A New Path for Vasculitis Treatment: Biological Agents

This research suggests that [研究結果] which could improve the management of vasculitis. It’s like discovering a hidden oasis in the desert of vasculitis treatment. The researchers’ findings highlight the potential of biological agents for specific types of vasculitis, but further research is needed to establish definitive guidelines for their use.

Living with Vasculitis: What You Should Know

This study reminds us that [健康的なベネフィットもしくはリスク] and that seeking professional help is essential for managing this condition. It’s like navigating a treacherous desert – you need the right tools and support to stay safe and healthy. If you are experiencing symptoms of vasculitis, talk to your doctor about your treatment options and explore new therapies that might be available.

Dr.Camel's Conclusion

This research is a testament to the ever-evolving landscape of medicine. Scientists are constantly seeking new and innovative approaches to treat complex diseases. Like a camel traversing a vast and unforgiving desert, we must always be open to new discoveries and adapt to the changing landscape of medical knowledge. This research provides valuable insights into the potential of biological agents for treating vasculitis, and it encourages us to continue exploring these promising avenues for improving patient care.

Date :
  1. Date Completed 2015-09-30
  2. Date Revised 2020-03-06
Further Info :

Pubmed ID

25517966

DOI: Digital Object Identifier

PMC4269410

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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