Efficacy of combined treatment with alendronate (ALN) and eldecalcitol, a new active vitamin D analog, compared to that of concomitant ALN, vitamin D plus calcium treatment in Japanese patients with primary osteoporosis.

Author: , FukudaF, IkedaS, InoueT, ItoM, MizunumaH, NakamuraT, SaitoH, SakaiA, TomomitsuT, TsurukamiH

Paper Details 
Original Abstract of the Article :
UNLABELLED: Combined treatment with alendronate and eldecalcitol was found to be more effective in reducing the bone turnover markers and increasing bone mineral density than alendronate treatment with vitamin D3 and calcium supplementation in the osteoporotic patients. INTRODUCTION: We compared th...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331603/

データ提供:米国国立医学図書館(NLM)

Boosting Bone Health: Alendronate and Eldecalcitol in Osteoporosis

This research ventures into the field of bone health, specifically focusing on the effectiveness of combined treatment with alendronate, a bisphosphonate medication, and eldecalcitol, a new active vitamin D analog, for managing osteoporosis. Osteoporosis, a condition characterized by weakened bones, is a major health concern, particularly in older adults. This study, conducted on Japanese patients with primary osteoporosis, compared the efficacy of combined alendronate and eldecalcitol treatment with a standard regimen of alendronate, vitamin D, and calcium supplementation. The researchers found that the combination of alendronate and eldecalcitol resulted in greater reductions in bone turnover markers and improvements in bone mineral density, making it a potentially more effective treatment option for osteoporosis.

Unlocking the Potential of Vitamin D Analogs

This research highlights the potential benefits of utilizing vitamin D analogs, like eldecalcitol, in managing osteoporosis. The study's findings suggest that eldecalcitol, when combined with alendronate, may enhance bone health by effectively modulating bone turnover and promoting bone mineral density. This finding opens new avenues for exploring the role of vitamin D analogs in osteoporosis treatment.

Building Stronger Bones for a Healthier Future

This research offers valuable insights into the management of osteoporosis, highlighting the potential benefits of combined alendronate and eldecalcitol therapy. The study's findings suggest that this combination may offer a more effective and comprehensive approach to improving bone health, ultimately contributing to a reduced risk of fractures and improved quality of life for individuals with osteoporosis.

Dr.Camel's Conclusion

This research looked at different treatment strategies for osteoporosis, a condition that weakens bones. They compared combining alendronate, a common medication, with a new type of vitamin D called eldecalcitol to the standard treatment with alendronate, regular vitamin D, and calcium. They found that the combination of alendronate and eldecalcitol resulted in greater improvement in bone health, suggesting that this combination could be a more effective treatment for osteoporosis.
Date :
  1. Date Completed 2015-12-21
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

25592133

DOI: Digital Object Identifier

PMC4331603

Related Literature

SNS
PICO Info
in preparation
Languages

English

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