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The use of anxiolytic and parasympathomimetic agents in the treatment of postoperative urinary retention following anorectal surgery. A prospective, randomized, double-blind study.

Author: GottesmanL, MazierW P, MilsomJ W

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This randomized, double-blind trial investigated the effectiveness of midazolam (an anxiolytic) and bethanechol (a parasympathomimetic) in reducing postoperative urinary retention after anorectal surgery. Bethanechol significantly reduced the incidence of retention, while midazolam had no effect. The study suggests that bethanechol should be considered as the initial treatment for postoperative urinary retention after anorectal surgery.
Paper Details　
Original Abstract of the Article :
Approximately 30 percent of patients undergoing anorectal surgery will develop acute urinary retention. The cause of this complication is poorly understood. Anxiety, anal distention, bladder distention as a result of vigorous hydration during surgery, and reflex inhibition of the urinary bladder det...See full text at original site
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引用元：
https://doi.org/10.1007/BF02554559

データ提供：米国国立医学図書館（NLM）

Exploring the Efficacy of Anxiolytic and Parasympathomimetic Agents in Postoperative Urinary Retention

This research delves into the field of [Postoperative Urinary Retention] following [Anorectal Surgery]. It employs a [Prospective, Randomized, Double-Blind Study] to assess the effectiveness of [Anxiolytic and Parasympathomimetic Agents] in reducing the incidence of this complication. The authors demonstrate [The Efficacy of Bethanechol] and highlight the [Lack of Effectiveness of Midazolam]. This study underscores the [Importance of Targeted Treatment Approaches] for postoperative urinary retention.

Bethanechol: A Promising Solution for Postoperative Urinary Retention

This research reveals that [Bethanechol effectively reduces the incidence of postoperative urinary retention]. The study found that [69% of patients responded to Bethanechol], highlighting its potential as a first-line treatment option. This finding provides a valuable tool for managing this common complication following anorectal surgery.

Understanding the Factors Contributing to Postoperative Urinary Retention

This research sheds light on [The potential contributing factors to postoperative urinary retention], including [Anxiety, Anal Distention, Bladder Distention, and Reflex Inhibition]. Understanding these factors can help healthcare professionals develop strategies to [Minimize the risk of postoperative urinary retention]. It emphasizes the need to [Address the underlying causes] rather than just treating the symptoms.

Dr. Camel's Conclusion

This research offers a valuable insight into the management of postoperative urinary retention. Just as a camel carefully navigates the shifting sands of the desert, this study helps us navigate the complexities of this complication. The research highlights the importance of targeted treatment strategies, with Bethanechol emerging as a promising option. This study underscores the importance of understanding the interplay of physiological factors and psychological influences in postoperative recovery.

Date :
  1. Date Completed 1989-11-14
  2. Date Revised 2019-07-21
Further Info :

Pubmed ID

2571469

DOI: Digital Object Identifier

10.1007/BF02554559

Related Literature

Article Analysis
・Side Effects of bethanechol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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