Paper Details

  1. Home
  2. Paper Details

The safety of amlodipine.

Author: OsterlohI

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Amlodipine is generally safe and well-tolerated. It has a favorable safety profile compared to beta-blockers, with a lower incidence of severe side effects. Amlodipine is not associated with unfavorable changes in serum cholesterol and triglycerides.
Paper Details　
Original Abstract of the Article :
The safety profile of amlodipine was assessed from the pooled data base of clinical research studies. This data base included 4227 subjects, 2495 of whom received amlodipine (including 2189 who received multiple-dose amlodipine); the remainder received comparative agents (placebo 1213; active compar...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/0002-8703(89)90838-7

データ提供：米国国立医学図書館（NLM）

Amlodipine: A Safe Oasis in the Desert of Hypertension

Hypertension, a silent killer, plagues millions across the globe. This study delves into the safety profile of amlodipine, a widely used drug for treating high blood pressure. Researchers meticulously analyzed data from clinical trials involving over 4200 subjects, comparing amlodipine to placebo and other antihypertensive agents. Their findings revealed that amlodipine exhibited a favorable safety profile, with a slightly higher incidence of side effects compared to placebo, mainly attributed to edema, which was generally well-tolerated. Amlodipine's safety profile was even more advantageous when compared to beta-blockers, showcasing a significantly lower incidence of severe side effects. This research, akin to finding a wellspring in a parched desert, underscores the safety and effectiveness of amlodipine as a cornerstone treatment for hypertension.

A Reliable Beacon in the Storm of Hypertension

The results of this study offer reassuring news to those seeking safe and effective hypertension management. Amlodipine emerges as a reliable beacon in the storm of hypertension, demonstrating a favorable safety profile compared to other antihypertensive agents. The study highlights the importance of carefully evaluating the safety of medications, ensuring they are both effective and well-tolerated. This research serves as a valuable guide for physicians and patients alike, fostering confidence in the use of amlodipine for managing high blood pressure.

A Oasis of Relief for Hypertension

This study provides a refreshing oasis of relief for those living with hypertension. Amlodipine emerges as a safe and effective treatment option, offering a sense of security and well-being. The favorable safety profile, particularly when compared to beta-blockers, is a significant advantage, minimizing the risk of adverse effects. This research is a testament to the ongoing pursuit of safer and more effective treatments for hypertension, offering a beacon of hope for a healthier future.

Dr. Camel's Conclusion

Amlodipine, my dear readers, is like a refreshing spring in the desert of hypertension. This study provides a reassuring glimpse into its safety profile, highlighting its effectiveness and minimal side effects. It stands as a valuable resource for physicians and patients, offering a beacon of hope for those seeking to navigate the challenges of high blood pressure.

Date :
  1. Date Completed 1989-12-06
  2. Date Revised 2019-06-26
Further Info :

Pubmed ID

2573265

DOI: Digital Object Identifier

10.1016/0002-8703(89)90838-7

Related Literature

Article Analysis
・Side Effects of nadolol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.