Tenofovir disoproxil fumarate is superior to lamivudine plus adefovir in lamivudine-resistant chronic hepatitis B patients.

Author: HuangHai-Jun, LiMing-Wei, PanHong-Ying, XieYuan-Jun, YangDan-Hong, ZhaoNian-Feng

Paper Details 
Original Abstract of the Article :
AIM: To assess the efficacy of tenofovir disoproxil fumarate (TDF) in lamivudine (LAM)-resistant patients with a suboptimal response to LAM plus adefovir (ADV). METHODS: We retrospectively analyzed the efficacy of switching to tenofovir disoproxil fumarate in suboptimal responders to lamivudine plu...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351227/

データ提供:米国国立医学図書館(NLM)

Tenofovir Disoproxil Fumarate for Lamivudine-Resistant Hepatitis B

Chronic hepatitis B, a persistent liver infection, is a challenging condition, much like a desert with a relentless heat that can cause lasting damage. This study compares the effectiveness of tenofovir disoproxil fumarate (TDF) to lamivudine plus adefovir (LAM plus ADV) in patients with lamivudine-resistant chronic hepatitis B.

The researchers, like desert scientists seeking a solution to a persistent drought, investigated the efficacy of TDF in patients with lamivudine-resistant chronic hepatitis B. Their findings suggest that TDF, like a life-giving spring in a parched desert, offers a more effective treatment option.

Tenofovir Disoproxil Fumarate: A Life-Giving Spring

The study found that switching to TDF monotherapy was superior to continuing LAM plus ADV in patients with lamivudine-resistant chronic hepatitis B. This discovery, like a oasis in the desert, provides a more effective treatment option for patients struggling with this condition. TDF demonstrated greater efficacy in reducing viral load and normalizing liver function.

Navigating the Desert of Hepatitis B Treatment

This study offers valuable insights into the management of lamivudine-resistant chronic hepatitis B. TDF, like a sturdy camel for a long desert journey, appears to be a more effective treatment option for these patients. Further research is needed to optimize treatment strategies and to understand the long-term implications of TDF therapy.

Dr.Camel's Conclusion

This study is a beacon of hope for patients with lamivudine-resistant chronic hepatitis B. TDF, like a refreshing oasis in the desert, offers a more effective treatment option, providing a potential pathway towards a healthier future.

Date :
  1. Date Completed 2015-09-28
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

25759545

DOI: Digital Object Identifier

PMC4351227

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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