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Severe adverse effects of bromocriptine in lactation inhibition: a pharmacovigilance survey.
Author: , BeckerM, BernardN, Bénard-LaribièreA, DescotesJ, JantzemH, MontastrucJ L, PecriauxC, VialT
Original Abstract of the Article :
OBJECTIVE: To assess the nature and conditions of the occurrence of adverse drug reactions (ADRs) of bromocriptine, which is used to inhibit lactation. DESIGN: Observational study. SETTING: Cases from the French pharmacovigilance database and the marketing authorisation holders. SAMPLE: Serious A...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/1471-0528.13352
データ提供:米国国立医学図書館(NLM)
Bromocriptine: A Cautionary Tale in the Desert of Lactation Inhibition
The [pharmacovigilance] landscape is constantly evolving, seeking to identify and mitigate the risks associated with medications. This study examines the serious adverse effects of bromocriptine, a drug used to inhibit lactation. The authors analyzed data from the French pharmacovigilance database and marketing authorization holders to assess the nature and conditions of the occurrence of adverse drug reactions (ADRs) associated with bromocriptine.
A Hidden Oasis: Bromocriptine's Potential Risks
The research reveals that bromocriptine can cause severe ADRs, including two fatal cases. The most frequent ADRs were cardiovascular, neurological, and psychiatric disorders. Cardiovascular disorders, including stroke and myocardial infarction, were particularly concerning. The study emphasizes the importance of careful monitoring for early signs of ADRs and highlights the risk of misuse, such as continuing bromocriptine despite the occurrence of symptoms or failing to titrate the dosage gradually.
Navigating the Sands of Medication Safety
This study serves as a reminder of the importance of carefully weighing the risks and benefits of medications. It emphasizes the need for clinicians and patients to be vigilant in monitoring for potential ADRs and to use bromocriptine only when other options are unavailable. The study also underscores the significance of patient education and empowering individuals to actively participate in their healthcare decisions.
Dr. Camel's Conclusion
The desert of medication safety is fraught with hidden dangers. This study reveals the potential pitfalls of bromocriptine, a drug used to inhibit lactation. We must be mindful of the risks associated with medications and prioritize patient safety. As a camel who has traversed the desert, I know that even a seemingly safe oasis can conceal hidden dangers. We must proceed with caution and always be prepared to navigate the shifting sands of medication safety.
Date :
- Date Completed 2015-10-14
- Date Revised 2015-11-19
Further Info :
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