Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma.

Author: BacharierLeonard B, BadeElizabeth, BoehmerSusan J, ChinchilliVernon M, CovarRonina A, GeraldJoe K, GeraldLynn B, GuilbertTheresa W, Heidarian-RaissyHengameh, KellyH William, LemanskeRobert F, Malka-RaisJonathan, MartinezFernando D, MaugerDavid T, MorganWayne J, SorknessChristine A, StrunkRobert C, SzeflerStanley J, TaussigLynn M, VasquezMonica M, ZeigerRobert S

Paper Details 
Original Abstract of the Article :
BACKGROUND: Inhaled corticosteroids are recommended as first-line therapy for children with mild persistent asthma; however, specific patient characteristics may modify the treatment response. OBJECTIVE: Identify demographic, clinical, and atopic characteristics that may modify the inhaled corticos...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/25783161

データ提供:米国国立医学図書館(NLM)

Personalized Asthma Treatment: A Step Towards Precision Medicine

This research explores the variability in response to inhaled corticosteroid treatment among children with mild persistent asthma. The study investigates the association between demographic, clinical, and atopic characteristics and the effectiveness of beclomethasone therapy. The results identify several characteristics, including non-Hispanic ethnicity, positive aeroallergen skin test, elevated serum immunoglobulin E levels, and history of oral corticosteroid use, as potential markers of greater treatment benefit.

Tailoring Asthma Treatment for Better Outcomes

This research highlights the need for personalized asthma treatment strategies based on specific patient characteristics. The findings suggest that children with atopic asthma, or those with greater asthma burden, may experience greater benefit from beclomethasone therapy. This study is a step towards precision medicine in asthma management, potentially leading to more individualized and effective treatments.

Managing Asthma: A Personalized Approach

This research underscores the importance of tailoring asthma treatment to the individual needs of each patient. As a desert-dwelling creature, I've learned to adapt to different environments and conditions. Similarly, asthma treatment should be personalized to account for the unique characteristics of each patient. We can improve asthma management by recognizing the factors that influence treatment response and developing individualized care plans.

Dr.Camel's Conclusion

This research emphasizes the need for personalized asthma treatment strategies. By identifying markers of greater treatment benefit, we can move towards a more individualized approach to asthma management, leading to better outcomes for patients.

Date :
  1. Date Completed 2016-04-07
  2. Date Revised 2019-10-08
Further Info :

Pubmed ID

25783161

DOI: Digital Object Identifier

NIHMS662357

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.