Characterisation of a novel panel of polymorphic microsatellite loci for the liver fluke, Fasciola hepatica, using a next generation sequencing approach.

Author: AllenKatherine, CwiklinskiKrystyna, HodgkinsonJane E, LaCourseJames, PatersonSteve, WilliamsDiana J

Paper Details 
Original Abstract of the Article :
The liver fluke, Fasciola hepatica is an economically important pathogen of sheep and cattle and has been described by the WHO as a re-emerging zoonosis. Control is heavily reliant on the use of drugs, particularly triclabendazole and as a result resistance has now emerged. The population structure ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424948/

データ提供:米国国立医学図書館(NLM)

Understanding the Liver Fluke: A Journey Through the Desert of Parasitology

The world of parasitology is a vast desert, filled with fascinating but often challenging creatures. This study focuses on Fasciola hepatica, a liver fluke that poses significant economic threats to sheep and cattle, and has been identified as a re-emerging zoonosis by the World Health Organization. The study aims to develop a novel panel of polymorphic microsatellite loci for F. hepatica, using a next-generation sequencing approach, to better understand its population structure and facilitate the development of control measures.

Microsatellite Loci: A New Tool for Understanding Liver Fluke Population Structure

The study successfully identifies 15 polymorphic microsatellite loci, which can be used to investigate the population structure of F. hepatica. This valuable tool provides researchers with a more comprehensive understanding of the parasite's genetic diversity and its potential impact on host-parasite interactions and parasite control. The findings pave the way for more effective strategies to combat this economically important pathogen.

Navigating the Desert of Liver Fluke Infection: A Quest for Control

This research highlights the importance of understanding the population structure of parasites to effectively control their spread. The development of novel microsatellite markers provides a crucial tool for monitoring the genetic diversity of F. hepatica and detecting the emergence of drug resistance. By gaining a deeper understanding of the parasite's biology, we can develop more targeted and effective control measures, protecting livestock and human health from the threat of liver fluke infection.

Dr.Camel's Conclusion

This study presents a novel panel of polymorphic microsatellite loci for the liver fluke, Fasciola hepatica, which can be used to investigate the population structure of this important pathogen. The development of these markers provides a valuable tool for researchers and practitioners to better understand the parasite's genetic diversity and facilitate the development of more effective control measures.

Date :
  1. Date Completed 2016-02-25
  2. Date Revised 2019-01-08
Further Info :

Pubmed ID

25796359

DOI: Digital Object Identifier

PMC4424948

Related Literature

SNS
PICO Info
in preparation
Languages

English

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