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Captopril and hydrochlorothiazide in the fixed combination multicenter trial.

Author: LederleR M

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

Low-dose captopril combined with hydrochlorothiazide is effective in lowering blood pressure and reducing side effects.
Paper Details　
Original Abstract of the Article :
The severe side effects uncommonly seen with captopril seem to be associated with high doses and/or compromised patients. A very flat dose-response curve in high dosages and the expectation of fewer side effects made us combine low-dose captopril with enhanced stimulation of the renin-angiotensin-al...See full text at original site
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引用元：
https://doi.org/10.1097/00005344-198507001-00013

データ提供：米国国立医学図書館（NLM）

Captopril and Hydrochlorothiazide: A Fixed Combination for Blood Pressure Control

In the realm of cardiovascular health, controlling high blood pressure is akin to navigating the scorching sands of a desert. This study explores the effectiveness of a fixed combination of captopril, a drug that blocks the production of a hormone that constricts blood vessels, and hydrochlorothiazide, a diuretic that helps remove excess fluid from the body. This combination, like a well-equipped caravan, aims to effectively lower blood pressure in patients who have not responded well to other treatments. The researchers investigated the effectiveness of this combination in patients with high blood pressure, finding that it led to significant reductions in both systolic and diastolic blood pressure.

A Powerful Combination: Captopril and Hydrochlorothiazide

The study demonstrates the effectiveness of this fixed combination in lowering blood pressure. The researchers found that it was successful in lowering blood pressure in patients who had not responded well to other treatments. This suggests that this combination could be a valuable tool for managing hypertension in patients who require additional support.

Managing High Blood Pressure: A Journey of Collaboration

High blood pressure is a serious condition that can lead to various health problems. This study highlights the importance of managing this condition through a collaborative approach, involving healthcare professionals and patients. Working closely with your doctor to determine the best treatment plan for your individual needs can help you navigate the desert of high blood pressure with confidence and success.

Dr.Camel's Conclusion

This study provides valuable insights into the potential of captopril and hydrochlorothiazide as a fixed combination for blood pressure control. Like a well-equipped caravan, this combination offers a powerful approach to managing hypertension. Remember, the journey of managing high blood pressure is a partnership between you and your healthcare provider.

Date :
  1. Date Completed 1985-05-20
  2. Date Revised 2019-07-24
Further Info :

Pubmed ID

2580179

DOI: Digital Object Identifier

10.1097/00005344-198507001-00013

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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