Treatment satisfaction and clinically meaningful symptom improvement in men with lower urinary tract symptoms and prostatic enlargement secondary to benign prostatic hyperplasia: Secondary results from a 6-month, randomized, double-blind study comparing finasteride plus tadalafil with finasteride plus placebo.

Author: CasabéAdolfo, GlinaSidney, HennegesCarsten, RoehrbornClaus G, SorsaburuSebastian, ViktrupLars

Overview

Coadministration of tadalafil 5 mg with finasteride 5 mg resulted in significantly more patients achieving early clinical meaningful improvements in symptoms and greater treatment satisfaction than finasteride alone in men with prostatic enlargement due to benign prostatic hyperplasia.

Paper Details　

Original Abstract of the Article :

OBJECTIVES: To report the secondary analyses of treatment satisfaction and clinically meaningful improvements in a randomized study comparing coadministration of tadalafil 5 mg with finasteride 5 mg versus finasteride alone in men with prostatic enlargement secondary to benign prostatic hyperplasia....See full text at original site

Dr.Camel's Paper Summary Blog

Treatment Satisfaction in Men with Lower Urinary Tract Symptoms

This study compares the treatment satisfaction and symptom improvement in men with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) treated with finasteride plus tadalafil versus finasteride plus placebo. The researchers found that coadministration of tadalafil with finasteride resulted in significantly more patients achieving clinically meaningful symptom improvements and higher treatment satisfaction.

Optimizing Treatment for LUTS

This research highlights the potential benefits of combining finasteride with tadalafil for treating LUTS in men with BPH. The researchers' findings suggest that this combination may lead to improved symptom relief and greater patient satisfaction.

Finding Relief in the Desert of LUTS

The researchers likened the challenge of managing LUTS to navigating a vast and arid desert. Just as a traveler seeks relief from the heat and thirst, men with LUTS seek relief from their symptoms. This study provides valuable insights into the potential of combining finasteride with tadalafil, offering a promising approach for alleviating LUTS and improving quality of life.

Dr.Camel's Conclusion

This study demonstrates the potential benefits of combining finasteride with tadalafil for treating lower urinary tract symptoms in men with benign prostatic hyperplasia. The researchers' findings highlight the importance of considering treatment satisfaction and clinically meaningful symptom improvements when developing therapeutic strategies for this common condition. This research underscores the need for individualized treatment approaches to optimize outcomes and improve the quality of life for men with LUTS.