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Skin metabolism established with the use of MetaSite for selected retinoids employed in topical and systemic treatment of various skin disorders and found in cosmeceuticals.
Author: Gunia-KrzyżakAgnieszka, MaronaHenryk, SłoczyńskaKarolina, WaszkielewiczAnna M, ŻelaszczykDorota
Original Abstract of the Article :
Besides being widely used in cosmetics, retinoids are potent therapeutic agents used topically and systemically as anti-acne agents. The aim of this study was to predict with the use of MetaSite the skin metabolism of selected retinoids employed in treatment of skin disorders and found in cosmeceuti...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.18388/abp.2014_891
データ提供:米国国立医学図書館(NLM)
Retinoids: Skin-Deep Secrets Revealed
Retinoids are like skincare superheroes, capable of tackling a range of skin issues. But, understanding how these powerful compounds work in the intricate world of [skin metabolism] is like navigating a vast desert—full of hidden complexities. This study aimed to unlock these secrets by using a tool called MetaSite, a powerful computational method for predicting how retinoids are processed by our skin.
MetaSite: A Computational Oasis for Retinoid Research
Using MetaSite, the researchers delved into the fate of nine different retinoids, including [retinol, retinaldehyde, retinoic acid, retinyl acetate, retinyl palmitate, acitretin, etretinate, adapalene and bexarotene]. This comprehensive analysis provides valuable insights into how these retinoids are transformed within our skin, paving the way for more effective skincare solutions.
Skin-Deep Insights for Skincare Solutions
The study's findings could lead to the development of new, tailored retinoid formulations for various skin conditions. By understanding how different retinoids behave within the skin, we can potentially optimize their effectiveness and minimize any potential side effects.
Dr.Camel's Conclusion
Just as a desert oasis provides a welcome respite for weary travelers, MetaSite offers a valuable resource for navigating the complex world of retinoid metabolism. This research opens up new avenues for developing smarter and more effective skincare solutions, making our skin healthier and more radiant.
Date :
- Date Completed 2016-04-28
- Date Revised 2018-12-03
Further Info :
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