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The role of surgery in the combined treatment of locally advanced breast cancer.

Author: AmorosoD, BattistiniG, BertelliG, CanaveseG, CarotiC, CatturichA, ConteP F, GardinG, PronzatoP, TomaoS

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated a combined treatment approach for 60 patients with advanced stage breast cancer. After three cycles of chemotherapy, 74.5% of patients experienced tumor shrinkage, and 98.3% were free of detectable disease after surgery or radiation. At four years, 71.5% of patients were alive, and 43% were disease-free. These results are significantly better than previous treatment outcomes and suggest that advanced breast cancer can now be considered a potentially curable disease with aggressive, multi-modal therapy.
Paper Details　
Original Abstract of the Article :
Sixty patients with stage IIIA and IIIB breast cancer have been treated with a combined modality approach including induction chemotherapy, surgery and adjuvant chemotherapy: 74.5% of patients achieved an objective response after 3 cycles of induction chemotherapy, and 98.3% of patients were rendere...See full text at original site
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引用元：
https://doi.org/10.1159/000226749

データ提供：米国国立医学図書館（NLM）

Conquering Locally Advanced Breast Cancer: A Multifaceted Approach

The fight against breast cancer is a complex and often arduous journey, requiring a multifaceted approach to treatment. This research explores the effectiveness of a combined modality approach to treating locally advanced breast cancer. The study analyzes the outcomes of a group of patients who underwent a rigorous treatment regimen involving induction chemotherapy, surgery, and adjuvant chemotherapy. The results demonstrate a significant improvement in survival rates and disease-free survival compared to historical controls, suggesting that locally advanced breast cancer can be considered a curable disease when treated with an aggressive multimodal approach.

A Collaborative Battle Against Cancer

The study highlights the importance of a multidisciplinary approach to treating locally advanced breast cancer. The results demonstrate that combining different treatment modalities, such as chemotherapy, surgery, and radiation therapy, can lead to significantly improved outcomes for patients. The research emphasizes the need for a collaborative effort between oncologists, surgeons, and other healthcare professionals to optimize treatment plans and maximize patient survival rates.

Hope on the Horizon

The study offers a glimmer of hope for individuals facing locally advanced breast cancer. The findings underscore the importance of early detection, aggressive treatment, and a multidisciplinary approach to achieving a positive outcome. The research inspires a sense of optimism, reminding us that progress is being made in the fight against breast cancer, and that with continued innovation and collaboration, we can make a significant difference in the lives of patients facing this challenging disease.

Dr.Camel's Conclusion

This research is a testament to the power of collaboration and innovation in the fight against breast cancer. By embracing a multidisciplinary approach and implementing rigorous treatment protocols, we can transform locally advanced breast cancer from a potentially fatal disease to a curable condition. The study's findings offer a beacon of hope for patients facing this challenge, reminding them that even in the face of adversity, there is always hope for a brighter future.

Date :
  1. Date Completed 1990-01-04
  2. Date Revised 2018-02-16
Further Info :

Pubmed ID

2587002

DOI: Digital Object Identifier

10.1159/000226749

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Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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