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Magnitude of effect of asthma treatments on Asthma Quality of Life Questionnaire and Asthma Control Questionnaire scores: Systematic review and network meta-analysis.

Author: BatemanEric D, ChirilaCostel, EsserDirk, FernandezMaria, FitzGeraldJ Mark, FowlerAndy, Moroni-ZentgrafPetra

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Two commonly used asthma questionnaires, the AQLQ and ACQ, often don't show significant improvements in patients taking new asthma medications compared to those on placebo, especially when the new drug is added to existing treatments. This means the improvements are not large enough to be considered clinically meaningful.
Paper Details　
Original Abstract of the Article :
The Asthma Quality of Life Questionnaire (AQLQ) and the Asthma Control Questionnaire (ACQ) are widely used in asthma research; however, in studies of newer asthma treatments, mean improvements in these measures compared with placebo arms do not exceed the minimal important difference (MID), particul...See full text at original site
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引用元：
https://doi.org/10.1016/j.jaci.2015.03.023

データ提供：米国国立医学図書館（NLM）

Assessing the Impact of Asthma Treatments

Asthma, a chronic respiratory condition, affects millions worldwide, impacting quality of life and requiring ongoing management. This study examines the effectiveness of various asthma treatments, evaluating their impact on asthma-related quality of life and control. The researchers conducted a systematic review and network meta-analysis to compare the effects of different treatments on two widely used asthma assessment tools: the Asthma Quality of Life Questionnaire (AQLQ) and the Asthma Control Questionnaire (ACQ).

A Detailed Comparison of Asthma Therapies

The meta-analysis revealed that while many newer asthma treatments showed improvements in AQLQ and ACQ scores compared to placebo, these improvements often did not exceed the minimal important difference. This finding suggests that while these treatments may provide some benefit, their impact on overall asthma control and quality of life might be limited, especially when added to existing therapies.

Navigating Asthma Management

This study highlights the importance of individualizing asthma treatment plans, taking into account each patient's specific needs and response to therapy. Healthcare providers should carefully evaluate the benefits and limitations of different treatment options to ensure the most effective and personalized care for each patient.

Dr.Camel's Conclusion

Just as a camel adapts to the changing desert environment, researchers are constantly seeking to optimize asthma management. This study provides valuable insights into the effectiveness of various asthma treatments, emphasizing the need for a personalized approach to ensure the best possible outcomes for each patient.

Date :
  1. Date Completed 2016-01-22
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25936565

DOI: Digital Object Identifier

10.1016/j.jaci.2015.03.023

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・Effective treatment of asthma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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