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Vitamin D in Foot and Ankle Fracture Healing: A Literature Review and Research Design.

Author: BernhardAndrew, MatukJorge

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Vitamin D is important for calcium levels and bone health. While research has focused on vitamin D's role in preventing fractures, especially in women and people with osteoporosis, there is limited research on its effect on healing broken bones. Most studies include calcium in the treatment, making it difficult to isolate the effect of vitamin D. Animal studies have also been inconclusive. While some case reports are promising, further research is needed to confirm the benefits of vitamin D for fracture healing.
Paper Details　
Original Abstract of the Article :
Vitamin D is a generic name for a group of essential vitamins, or secosteroids, important in calcium homeostasis and bone metabolism. Specifically, efficacy of vitamin D with regard to bone healing is in question. A literature review was performed, finding mostly large studies involving vitamin D ef...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1177/1938640015585958

データ提供：米国国立医学図書館（NLM）

Vitamin D and Bone Healing: An Exploration

This study delves into the intricate world of [vitamin D] and its potential role in bone healing, particularly in the context of foot and ankle fractures. The researchers acknowledge the complexities of this topic, noting a lack of conclusive evidence regarding the efficacy of vitamin D supplementation in promoting bone healing. The study examines the current research landscape, revealing a need for more robust and focused research to address this gap in our understanding.

Current Research and Challenges

The study identifies a key challenge in the existing research: a limited number of studies directly examining the impact of vitamin D on fracture healing. Many studies focus on vitamin D's role in preventing fractures or explore the effects of vitamin D supplementation in animal models, but these studies often include calcium in the treatment regimen, making it difficult to isolate the specific effects of vitamin D. This highlights the need for well-designed human studies that specifically evaluate the effects of vitamin D on fracture healing.

A Proposed Research Design for Clarifying the Role of Vitamin D

The study proposes a novel research design that could provide more definitive answers regarding the efficacy of vitamin D in promoting fracture healing. The researchers suggest a controlled study with a larger sample size, focusing on the effects of vitamin D supplementation alone, without the inclusion of calcium. This approach would allow for a more precise evaluation of the role of vitamin D in bone healing, paving the way for a better understanding of its potential therapeutic benefits in fracture management.

Dr.Camel's Conclusion

This study serves as a valuable reminder that the role of vitamin D in bone healing is still not fully understood. The researchers' call for more rigorous research is crucial to clarifying this complex issue. As we continue to unravel the intricate relationship between vitamin D and bone health, we can develop more effective strategies for promoting bone healing and improving patient outcomes.

Date :
  1. Date Completed 2016-06-21
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25964289

DOI: Digital Object Identifier

10.1177/1938640015585958

SNS
PICO Info
in preparation
Languages

English

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