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Response of bone turnover markers to three oral bisphosphonate therapies in postmenopausal osteoporosis: the TRIO study.
Author: EastellR, GossielF, JacquesR M, McCloskeyE V, NaylorK E, PaggiosiM, PeelN F A, WalshJ S
Original Abstract of the Article :
We used bone turnover markers to identify women who responded to bisphosphonate treatment for osteoporosis. Response was more likely with alendronate and ibandronate than risedronate. There was a greater decrease in bone markers if baseline bone turnover markers were higher and if the patient took m...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s00198-015-3145-7
データ提供:米国国立医学図書館(NLM)
Bisphosphonates for Osteoporosis: A Journey Through the Desert of Bone Health
The desert of bone health is a fascinating landscape, constantly evolving and responding to various influences. This study, like a scientific expedition, explores the effects of three oral bisphosphonates, a class of drugs commonly used to treat osteoporosis, on bone turnover markers in postmenopausal women.The Impact of Bisphosphonates on Bone Metabolism
The researchers, like careful desert guides, analyzed the response of bone turnover markers, indicators of bone formation and breakdown, to different bisphosphonates. Their findings, like a well-defined oasis in the desert, revealed that alendronate and ibandronate were more likely to elicit a positive response than risedronate. The study also emphasized the importance of medication adherence and the correlation between baseline bone turnover markers and treatment response.The Quest for Personalized Bone Health
This research underscores the need for individualized treatment strategies for osteoporosis. Just like a desert traveler needs to adapt to the changing landscape, each individual’s bone health is unique and requires a personalized approach. This study highlights the importance of careful monitoring of bone turnover markers, a key tool in the quest for optimal bone health.Dr. Camel’s Conclusion
This study, like a fascinating desert exploration, reveals the complexities of bone health and the importance of personalized treatment. It emphasizes the need for ongoing research, like a tireless caravan trek, to further refine our understanding of osteoporosis and its management. By embracing a collaborative approach and applying evidence-based medicine, we can navigate the desert of bone health with confidence and success.Date :
- Date Completed 2016-10-24
- Date Revised 2022-04-08
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