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A Randomized Controlled Trial of Intravenous Haloperidol vs. Intravenous Metoclopramide for Acute Migraine Therapy in the Emergency Department.

Author: BrunerDavid I, FrumkinKenneth, GaffiganMatthew E, PritchardAmy, WasonCourtney

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Intravenous haloperidol was as safe and effective as metoclopramide for the treatment of migraine headaches in the emergency department. It resulted in similar pain relief and required less frequent rescue medications.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Emergency Department (ED) headache patients are commonly treated with neuroleptic antiemetics like metoclopramide. Haloperidol has been shown to be effective for migraine treatment. STUDY OBJECTIVE: Our study compared the use of metoclopramide vs. haloperidol to treat ED migraine patien...See full text at original site
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引用元：
https://doi.org/10.1016/j.jemermed.2015.03.023

データ提供：米国国立医学図書館（NLM）

Haloperidol vs. Metoclopramide for Acute Migraine Treatment: A Randomized Controlled Trial

This research investigates the efficacy of intravenous haloperidol compared to intravenous metoclopramide for the treatment of acute migraine headaches in emergency department (ED) settings. The study employed a randomized, double-blinded design to compare the effectiveness of these two medications in reducing pain, nausea, and other migraine symptoms. The researchers carefully analyzed pain scores, side effects, and patient satisfaction to determine the optimal treatment approach for migraine headaches in the ED.

Haloperidol: An Effective and Safe Treatment for Migraine

This research demonstrates that intravenous haloperidol is as safe and effective as metoclopramide for the treatment of acute migraine headaches in ED settings. The study found that both medications effectively reduced pain and nausea, with similar time to maximum improvement. Importantly, haloperidol led to a significantly lower need for rescue medications, suggesting that it may be a more effective treatment option for some patients.

Managing Migraine Headaches in the Emergency Department

This research offers valuable guidance for emergency physicians seeking effective and safe treatment options for patients with acute migraine headaches. The study's findings suggest that intravenous haloperidol is a viable alternative to metoclopramide, offering comparable pain relief with fewer side effects and a lower need for rescue medications.

Dr.Camel's Conclusion

This research is a welcome addition to the field of migraine management, offering evidence-based support for the use of intravenous haloperidol as a safe and effective treatment option for acute migraine headaches in the ED. The study's findings provide valuable insights for healthcare providers seeking to optimize migraine care and improve patient outcomes.
Date :
  1. Date Completed 2016-05-23
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

26048068

DOI: Digital Object Identifier

10.1016/j.jemermed.2015.03.023

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Article Analysis
・Effective treatment of headache
SNS
PICO Info
in preparation
Languages

English

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