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The Effect of Memantine on Cognitive Function and Behavioral and Psychological Symptoms in Mild-to-Moderate Alzheimer's Disease Patients.

Author: ChengYan, DuHongjian, ShiFu-Dong, WeiChangjuan, ZhangNan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Memantine is effective for the treatment of mild-to-moderate AD, especially in patients with agitation.
Paper Details　
Original Abstract of the Article :
BACKGROUND/AIMS: Memantine has been approved by the Food and Drug Administration for the treatment of moderate-to-severe Alzheimer's disease (AD). However, the effect of memantine on patients with mild-to-moderate AD is unclear. METHODS: This study is a post hoc analysis of a double-blind clinical ...See full text at original site
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引用元：
https://doi.org/10.1159/000430808

データ提供：米国国立医学図書館（NLM）

Exploring New Horizons in Alzheimer's Disease Treatment

Alzheimer's disease (AD), a progressive neurodegenerative disorder, poses a formidable challenge for patients and healthcare professionals alike. This study, like a desert explorer seeking a more effective path through a challenging landscape, investigates the potential of memantine, a drug that targets the NMDA receptor, in treating mild-to-moderate AD.

Memantine: A Potential Oasis in the Desert of Alzheimer's Disease

The study's findings suggest that memantine can be effective in managing mild-to-moderate AD, particularly in patients experiencing agitation. This discovery, like finding a hidden spring in the arid desert, offers hope for patients seeking relief from the debilitating symptoms of AD.

Dr. Camel's Conclusion

This research provides valuable insights into the potential benefits of memantine in treating mild-to-moderate AD. The study's findings suggest that memantine, particularly effective in managing agitation, offers a promising avenue for exploring new treatment options for patients with AD. This research, like a guidebook for navigating the complexities of AD, offers valuable information for healthcare professionals and patients alike.

Date :
  1. Date Completed 2016-01-15
  2. Date Revised 2018-12-03
Further Info :

Pubmed ID

26066622

DOI: Digital Object Identifier

10.1159/000430808

Related Literature

Article Analysis
・Effective treatment of alzheimer's disease
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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