Neuroleptic malignant syndrome in cycloserine-induced psychosis.

Author: BhatankarSwaroop S, KateNatasha S, KulkarniPrathamesh S, SawantNeena S

Paper Details 
Original Abstract of the Article :
A 33-year-old multidrug-resistant tuberculosis female patient diagnosed as cycloserine-induced psychosis developed several neuroleptic side effects such as extrapyramidal reaction, neuroleptic malignant syndrome, and drug-induced parkinsonism while she was being treated with initially haloperidol an...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450562/

データ提供:米国国立医学図書館(NLM)

Neuroleptic Malignant Syndrome: A Case Study of Drug Interactions

Drug interactions can sometimes have unexpected consequences, especially in complex medical situations like multidrug-resistant tuberculosis. This study investigates a case where a 33-year-old woman, diagnosed with cycloserine-induced psychosis, developed a serious neuroleptic side effect known as neuroleptic malignant syndrome. The study delves into the patient's response to different antipsychotic medications, including haloperidol and olanzapine, and ultimately, her recovery with bromocriptine treatment. This case highlights the importance of careful monitoring and adjustment of medication regimens in patients with complex medical histories.

Neuroleptic Malignant Syndrome: A Serious Side Effect

Neuroleptic malignant syndrome is a rare but potentially life-threatening condition that can occur as a side effect of certain medications, especially antipsychotics. In this case, the patient developed neuroleptic malignant syndrome as a result of being treated with haloperidol and then olanzapine. The study demonstrates the importance of closely monitoring patients for signs and symptoms of neuroleptic malignant syndrome, such as muscle rigidity, fever, and altered mental status.

Managing Drug Interactions: A Balancing Act

This case study emphasizes the challenges of managing drug interactions in patients with complex medical conditions. It highlights the need for a comprehensive understanding of each patient's individual medical history and the potential side effects of medications. It also emphasizes the importance of recognizing and responding promptly to any adverse reactions, such as neuroleptic malignant syndrome, to ensure optimal patient outcomes.

Dr.Camel's Conclusion

This study provides valuable insights into the complexities of drug interactions in multidrug-resistant tuberculosis. The patient's experience serves as a reminder that drug interactions can be unpredictable and potentially life-threatening, even when seemingly safe medications are used. The case illustrates the importance of carefully considering the potential benefits and risks of all medications before prescribing them, especially in patients with complex medical conditions.

Date :
  1. Date Completed 2016-05-09
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

26069374

DOI: Digital Object Identifier

PMC4450562

Related Literature

SNS
PICO Info
in preparation
Languages

English

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