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Comparative effects of hawthorn (Crataegus pinnatifida Bunge) pectin and pectin hydrolyzates on the cholesterol homeostasis of hamsters fed high-cholesterol diets.

Author: ChenGang, DuanWen-Bin, JinXiao-Yi, LiTuo-Ping, LiuYan-Hua, PengXue, ShiShu-Lei, SunYan-Di, XuJing-Guo, ZhengZheng-Zheng, ZhuRu-Gang

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Hawthorn pectin pentasaccharide (HPPS) was more effective than other forms of hawthorn pectin at reducing body weight, liver weight, and cholesterol levels in hamsters with high cholesterol.
Paper Details　
Original Abstract of the Article :
This study aims to compare the effects of feeding haw pectin (HP), haw pectin hydrolyzates (HPH), and haw pectin pentasaccharide (HPPS) on the cholesterol metabolism of hypercholesterolemic hamsters induced by high-cholesterol diets. The animals were fed a standard diet (SD), high-cholesterol diet (...See full text at original site
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引用元：
https://doi.org/10.1016/j.cbi.2015.06.006

データ提供：米国国立医学図書館（NLM）

Hawthorn Pectin: A Potential New Weapon in the Fight Against High Cholesterol

This study explores the potential cholesterol-lowering effects of hawthorn pectin (HP) and its hydrolyzed forms. The researchers investigated the impact of these pectin derivatives on cholesterol homeostasis in hamsters fed a high-cholesterol diet.

Hawthorn Pectin Hydrolyzates: A Promising Cholesterol-Lowering Agent

The study reveals that hawthorn pectin pentasaccharide (HPPS), a hydrolyzed form of HP, was more effective than HP and other hydrolyzates in reducing body weight gain, liver weight, and both plasma and hepatic total cholesterol levels in hamsters. This suggests that HPPS may offer a promising strategy for managing high cholesterol.

Understanding the Role of Pectin in Cholesterol Metabolism

This research sheds light on the potential of pectin derivatives to regulate cholesterol metabolism. The study's findings suggest that specific pectin hydrolyzates may be more effective than intact pectin in lowering cholesterol levels. As Dr. Camel, I am always fascinated by the intricate ways in which dietary components can influence our health. This study provides valuable insights into the role of pectin in cholesterol management.

Dr.Camel's Conclusion

This study provides evidence that hawthorn pectin pentasaccharide may be a promising dietary ingredient for lowering cholesterol levels. Further research is needed to confirm these findings and explore the potential of HPPS for developing functional foods to improve cholesterol metabolism.

Date :
  1. Date Completed 2015-10-20
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26070415

DOI: Digital Object Identifier

10.1016/j.cbi.2015.06.006

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Languages

English

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