Effective treatment of hawthorn: A Synthesis of Findings from 23 Studies

  1. Home
  2. Effective treatment of hawthorn
This information is not medical advice and is not a substitute for diagnosis or treatment by a physician.Data sources and disclaimers (data limitations, copyright, etc.)The analysis on "Effective treatment of hawthorn: A Synthesis of Findings from 23 Studies" on this page is based on PubMed data provided by the U.S. National Library of Medicine (NLM). However, NLM does not endorse or verify these analyses.

This analysis is based on research papers included in PubMed, but medical research is constantly evolving and may not fully reflect the latest findings. There may also be biases towards certain research areas.

This information is not medical advice and is not a substitute for diagnosis or treatment by a physician. If you have concerns about "Effective treatment of hawthorn: A Synthesis of Findings from 23 Studies", please consult your doctor.

For NLM copyright information, please see Link to NLM Copyright Page
PubMed data is obtained via Hugging Face Datasets: Link to DatasetPlease check the disclaimer.
This page's analysis is based on PubMed data provided by the U.S. National Library of Medicine (NLM).
Original Abstract of the Article

Major Research Findings

A comprehensive review of the Hawthorne effect suggests that research participation can influence behavior, but this effect is typically small and highly dependent on the context of the study. 1 The study indicates that the Hawthorne effect arises from various factors such as increased attention to participants, greater involvement in the study, and enhanced social approval. 1 The magnitude of the Hawthorne effect varies depending on the study design, participant characteristics, and how the research is conducted. 1

Benefits and Risks

Benefit Summary

Studies on the Hawthorne effect have provided crucial insights into the impact of attention on participant behavior. 1 This knowledge can be utilized to improve research design, especially in intervention studies. 1 Researchers can employ strategies like refining study designs to minimize the Hawthorne effect or using random assignment of participants. 1

Risk Summary

The Hawthorne effect can introduce bias into research findings, leading to inaccurate conclusions. 1 To minimize the Hawthorne effect, researchers need to carefully design studies and be transparent with participants about their involvement in the research. 1

Comparison Across Studies

Commonalities Across Studies

Most studies on the Hawthorne effect suggest that increased attention to research participants can potentially influence behavior. 1 This effect is observed both when participants are aware of the study and when they are unaware. 1

Differences Across Studies

The magnitude of the Hawthorne effect varies across different studies. 1 This variability could be attributed to factors such as study design, participant characteristics, and how the research is conducted. 1

Consistency and Contradictions in Results

There is a mixture of consistency and contradictions in the research findings regarding the Hawthorne effect. 1 While some studies indicate a significant impact of increased attention on participants' behavior, others have not found such effects. 1 These discrepancies could be explained by differences in study design, participant characteristics, and how the research is implemented. 1

Considerations for Real-World Application

The Hawthorne effect has the potential to significantly impact real-life situations. 1 For instance, in studies about employee productivity, knowing that they are being monitored may lead to increased output. 1 However, the Hawthorne effect highlights that research findings may not always be accurate, thus requiring cautious interpretation of results. 1

Limitations of Current Research

Research on the Hawthorne effect is still evolving. 1 Further research is needed to effectively identify and measure the impact of the Hawthorne effect. 1

Future Directions for Research

Research on the Hawthorne effect needs to investigate the influence of various factors. 1 These factors include study design, participant characteristics, and the methods of conducting the research. 1 A better understanding of the impact of these factors can lead to the development of improved methods to minimize the influence of the Hawthorne effect. 1

Conclusion

The Hawthorne effect is a well-documented phenomenon that can influence research outcomes. 1 It is crucial for researchers to understand the ways to minimize the impact of the Hawthorne effect. 1 Further research is needed in the future to unravel the complex interactions of the Hawthorne effect and gain a more comprehensive understanding of its influence. 1

Literature analysis of 23 papers
Positive Content
20
Neutral Content
1
Negative Content
2
Article Type
2
0
1
3
23
1.

Systematic review of the Hawthorne effect: new concepts are needed to study research participation effects.

Author: McCambridgeJim, WittonJohn, ElbourneDiana R

Research artifact

The Hawthorne effect, a research artifact on behavior, was found to exist in most studies reviewed, but the conditions under which it operates, its mechanisms, and its magnitudes are uncertain.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

3.

Comparative effects of hawthorn (Crataegus pinnatifida Bunge) pectin and pectin hydrolyzates on the cholesterol homeostasis of hamsters fed high-cholesterol diets.

Author: ZhuRu-Gang, SunYan-Di, LiTuo-Ping, ChenGang, PengXue, DuanWen-Bin, ZhengZheng-Zheng, ShiShu-Lei, XuJing-Guo, LiuYan-Hua, JinXiao-Yi

Cholesterol metabolism

Hawthorn pectin pentasaccharide (HPPS) was more effective than other forms of hawthorn pectin at reducing body weight, liver weight, and cholesterol levels in hamsters with high cholesterol.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

4.

Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial.

Author: WalkerAnn F, MarakisGeorgios, SimpsonEleanor, HopeJessica L, RobinsonPaul A, HassaneinMohamed, SimpsonHugh C R

Diastolic BP reduction
Improved well-being
Micronutrient deficiencies

Hawthorn extract significantly reduced diastolic blood pressure in patients with type 2 diabetes who were taking medication for hypertension.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

7.

Composition and health effects of phenolic compounds in hawthorn (Crataegus spp.) of different origins.

Author: YangBaoru, LiuPengzhan

Anti-Inflammatory
Antioxidant
Cardioprotective
Hypolipidaemic
Hypotensive

Hawthorn is a plant that contains various phenolic compounds, including procyanidins, flavonol glycosides, and C-glycosyl flavones. This study reviewed the cardioprotective, hypolipidaemic, hypotensive, antioxidant, and anti-inflammatory effects of hawthorn extracts. More clinical studies are needed to confirm the effects of hawthorn in healthy humans.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

8.

The genotoxic effects of fruit extract of Crataegus oxyacantha (hawthorn) in mice.

Author: YonekuboBruna Thiemi, AlvesHeloisa de Miranda Cantuaria, de Souza MarquesEduardo, PerazzoFábio Ferreira, RosaPaulo César Pires, GaivãoIsabel O'Neill de Mascarenhas, MaistroEdson Luis

Cardiovascular health
Genotoxicity

Crataegus oxyacantha, commonly known as hawthorn, is a medicinal plant with a long history of use. This study investigated the genotoxic potential of hawthorn fruit extract in mice. The study found that hawthorn extract did not significantly induce DNA damage but did cause a significant increase in micronucleated erythrocytes, suggesting a possible clastogenic or aneugenic effect. The findings highlight the potential genotoxic effects of hawthorn extract and suggest caution with prolonged or high-dose use.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

11.

Effects of hawthorn ( Crataegus pentagyna) leaf extract on electrophysiologic properties of cardiomyocytes derived from human cardiac arrhythmia-specific induced pluripotent stem cells.

Author: PahlavanSara, TousiMarziyeh Shalchi, AyyariMahdi, AlirezaluAbolfazl, AnsariHassan, SaricTomo, BaharvandHossein

Antiarrhythmic potential

This study investigated the cardiac effects of hawthorn leaf extract using cardiomyocytes derived from healthy human embryonic stem cells, long QT syndrome type 2 (LQTS2), and catecholaminergic polymorphic ventricular tachycardia type 1 (CPVT1) patient-specific induced pluripotent stem cells.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

12.

Hawthorn ethanolic extracts with triterpenoids and flavonoids exert hepatoprotective effects and suppress the hypercholesterolemia-induced oxidative stress in rats.

Author: Rezaei-GolmishehAli, MalekinejadHassan, Asri-RezaeiSiamak, FarshidAmir Abbas, AkbariPeyman

Hawthorn extracts
Hepatoprotective effect
Hypocholesterolemic effect

Hawthorn extracts were effective in reducing hypercholesterolemia-induced oxidative stress and hepatic injuries in rats.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

13.

Effects of hawthorn seed and pulp extracts on the central nervous system.

Author: CanOzgür Devrim, OzkayUmide Demir, OztürkNilgün, OztürkYusuf

CNS depressant
Pain relief

Hawthorn fruit extracts (HPE and HSE) showed central nervous system (CNS) depressant activity and opioid-related analgesic effects in mice.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

14.

Effects on hawthorn the year after simulated spray drift.

Author: KjaerChristian, StrandbergMorten, ErlandsenMogens

Herbicide toxicity

This study investigated the effects of the herbicide metsulfuron-methyl on hawthorn trees. The herbicide significantly reduced the number of leaves, buds, flowers, green berries, and mature berries. This study highlights the potential for long-term effects of herbicides on perennial non-target plants in the spray drift zone.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

16.

A comparison of the effects of commercially available hawthorn preparations on calcium transients of isolated cardiomyocytes.

Author: RodriguezMichelle E, PoindexterBrian J, BickRoger J, DasguptaAmitava

Cardiac effects

Two commercially available hawthorn extracts demonstrated markedly different effects on isolated adult rat cardiomyocytes, with one extract causing calcium overload.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

17.

Effects of hawthorn seed oil on plasma cholesterol and gut microbiota.

Author: KwekErika, YanChi, DingHuafang, HaoWangjun, HeZouyan, LiuJianhui, MaKa Ying, ZhuHanyue, ChenZhen-Yu

Cardioprotective
Gut microbiota modulation
Hypocholesterolemic

Hawthorn is a plant that has been shown to reduce cholesterol levels. This study looked at the effects of hawthorn seed oil (HSO) in hamsters with high cholesterol. HSO reduced cholesterol levels and improved gut bacteria.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

18.

Scale-dependent effects of habitat fragmentation on hawthorn pollination, frugivory, and seed predation.

Author: GarcíaDaniel, ChacoffNatacha P

Plant regeneration
Habitat fragmentation

Habitat fragmentation negatively impacts plant regeneration by reducing pollination, frugivory, and increasing seed predation. Pollination and frugivory were negatively affected by habitat loss at larger scales, whereas seed predation was most affected at intermediate scales. These findings suggest that habitat fragmentation can have complex and cascading effects on plant regeneration.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

20.

Protective effects of hawthorn (Crataegus pinnatifida) polyphenol extract against UVB-induced skin damage by modulating the p53 mitochondrial pathway in vitro and in vivo.

Author: LiuSuwen, SuiQianqian, ZouJian, ZhaoYanxue, ChangXuedong

Protect against UVB damage

Hawthorn polyphenol extract (HPE) can be used as a natural dietary supplement for the prevention and treatment of UVB radiation-induced skin damage.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

21.

[Beneficial effects and related mechanism of hawthorn leaves flavonoids on cardiac function in rats with acute myocardial infarction].

Author: ZhangX H, LiuJ D, YuF W, WangD W

Cardiac function improvement

Hawthorn leaf flavonoids (FHL) were found to effectively improve cardiac function in rats with acute myocardial infarction (AMI). The beneficial effects were mediated through activating the PI3K/GSK3β/cyclin D1 signaling pathway.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Chinese

22.

Electrocardiographic effects of hawthorn (Crataegus oxyacantha) in healthy volunteers: A randomized controlled trial.

Author: TrexlerStephanie E, NguyenElaine, GromekSamantha M, BalunasMarcy J, BakerWilliam L

Hawthorn is a plant that has been used for many years to treat heart conditions. This study looked at whether hawthorn had any effects on the electrical activity of the heart.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.