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Evaluation of thiolated silicone oil as advanced mucoadhesive antifoaming agent.
Author: Bernkop-SchnürchAndreas, LeonaviciuteGintare, NetsomboonKesinee, PartenhauserAlexandra
Original Abstract of the Article :
CONTEXT: Silicone oils, such as dimethicone, are commonly administered against gastrointestinal gas accumulation and are attributed with mucoprotective features. OBJECTIVE: Evaluation of thiolated silicone oil as advanced antiflatulence with a prolonged retention on small intestinal mucosa as an in...See full text at original site
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引用元:
https://doi.org/10.3109/10717544.2015.1054051
データ提供:米国国立医学図書館(NLM)
Thiolated Silicone Oil: A New Hope for Gas and Inflammation in the Gut?
In the vast and often turbulent desert of the gastrointestinal tract, researchers are always searching for oases of relief, especially for those suffering from gas and inflammation. This study delves into the potential of thiolated silicone oil, a new contender in the fight against flatulence and its associated discomfort. Using innovative techniques, researchers investigated the ability of this modified silicone oil to quell foam formation, cling to the intestinal lining, and ultimately soothe the troubled gut. Their findings suggest that thiolated silicone oil may be a promising new tool for treating these common conditions.
A Mucoadhesive Marvel: Staying Power in the Gut
The researchers discovered that thiolated silicone oil possesses a remarkable ability to stick to the intestinal mucosa, unlike its non-thiolated counterpart. This clinging characteristic, known as mucoadhesion, allows the oil to remain in the gut for a significantly longer period, potentially amplifying its effectiveness in combating gas and inflammation. They observed that a whopping 26.2% of the thiolated silicone oil formulation lingered on the small intestinal mucosa after eight hours, a testament to its impressive staying power.
A Gentle Giant: No Toxicity, Just Relief
In the quest for a solution, safety is paramount. The good news? This thiolated silicone oil showed no signs of toxicity in the tests conducted. This suggests that it could be a safe and effective treatment option for individuals seeking relief from gastrointestinal discomfort.
Dr.Camel's Conclusion
This study presents a promising new avenue for managing gas and inflammation in the digestive system. It's like finding a refreshing oasis in the heart of a scorching desert, offering a much-needed respite from discomfort. The mucoadhesive properties of thiolated silicone oil may revolutionize the treatment of flatulence and intestinal inflammation, bringing a wave of relief to those who struggle with these conditions.
Date :
- Date Completed 2017-03-01
- Date Revised 2017-03-02
Further Info :
Related Literature
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