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Tedizolid: The First Once-Daily Oxazolidinone Class Antibiotic.

Author: BurdetteSteven D, TrotmanRobin

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Tedizolid phosphate is a novel oxazolidinone antibiotic that is dosed once daily and has been shown to be noninferior to linezolid for the treatment of acute bacterial skin and skin structure infections.
Paper Details　
Original Abstract of the Article :
Tedizolid phosphate is the second commercially available oxazolidinone antibiotic, although the first one in class that is dosed once daily. It is a prodrug that is rapidly converted to the active compound tedizolid. Tedizolid has activity against a wide range of gram-positive pathogens, including m...See full text at original site
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引用元：
https://doi.org/10.1093/cid/civ501

データ提供：米国国立医学図書館（NLM）

Tedizolid: A New Antibiotic for Skin Infections

The world of medicine is constantly evolving, my friend, searching for new ways to combat disease and alleviate suffering. This study introduces tedizolid, a new once-daily oxazolidinone antibiotic, and explores its effectiveness in treating skin infections.

Imagine a desert caravan, its members facing the threat of desert sores and infections. Tedizolid is like a potent ointment, a balm that heals wounds and fights off harmful bacteria. The researchers investigated tedizolid's efficacy in treating acute bacterial skin and skin structure infections (ABSSSIs), comparing it to linezolid, another oxazolidinone antibiotic.

Effective and Convenient Treatment

The study found that tedizolid was as effective as linezolid in treating ABSSSIs, but with the added advantage of a once-daily dosing regimen. It's like finding a shortcut through a desert, achieving the same outcome with less effort. This convenience can improve patient adherence to treatment, leading to better outcomes.

A Promising New Option

Tedizolid appears to have a favorable side-effect profile compared to linezolid, with fewer gastrointestinal and hematologic issues. It's like a camel that can navigate rough terrain with minimal risk of stumbling. This makes it a promising new option for treating skin infections, offering patients a safe and effective solution.

Dr.Camel's Conclusion

This study introduces tedizolid, a new once-daily oxazolidinone antibiotic, as an effective and convenient treatment for acute bacterial skin and skin structure infections. Its efficacy, safety, and ease of administration make it a valuable addition to the arsenal of antibiotics for fighting skin infections.

Date :
  1. Date Completed 2016-07-11
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

26105167

DOI: Digital Object Identifier

10.1093/cid/civ501

Related Literature

Article Analysis
・Side Effects of tedizolid
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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