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Trial of a Paclitaxel-Coated Balloon for Femoropopliteal Artery Disease.
Author: , BenenatiJames F, BrodmannMarianne, GammonRoger, JaffMichael R, KrishnanPrakash, Mena-HurtadoCarlos, MetzgerD Christopher, Müller-HülsbeckStefan, NehlerMark R, PilgerErnst, Rocha-SinghKrishna, RosenfieldKenneth, ScheinertDierk, WhiteChristopher J, ZellerThomas
Original Abstract of the Article :
BACKGROUND: The treatment of peripheral artery disease with percutaneous transluminal angioplasty is limited by the occurrence of vessel recoil and restenosis. Drug-coated angioplasty balloons deliver antiproliferative agents directly to the artery, potentially improving vessel patency by reducing r...See full text at original site
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引用元:
https://doi.org/10.1056/NEJMoa1406235
データ提供:米国国立医学図書館(NLM)
Paclitaxel-Coated Balloon: A Promising New Approach for Femoropopliteal Artery Disease
This study delves into the realm of [peripheral artery disease (PAD)] and investigates the effectiveness of a paclitaxel-coated balloon in treating femoropopliteal artery disease. The authors conducted a randomized controlled trial comparing angioplasty with a paclitaxel-coated balloon to standard angioplasty in 476 patients with symptomatic PAD. The primary efficacy endpoint was primary patency of the target lesion at 12 months. The results demonstrated that the paclitaxel-coated balloon resulted in a significantly higher rate of primary patency compared to standard angioplasty. Furthermore, the paclitaxel-coated balloon was noninferior to the standard balloon with respect to safety. This study offers compelling evidence for the effectiveness and safety of paclitaxel-coated balloons in treating femoropopliteal artery disease, providing a promising new option for patients with PAD.
Paclitaxel-Coated Balloons Show Promise in Treating Femoropopliteal Artery Disease
The study's findings suggest that paclitaxel-coated balloons represent a significant advance in the treatment of femoropopliteal artery disease. The improved primary patency rates and noninferior safety profile compared to standard angioplasty make this a promising new option for patients with PAD. This research has the potential to improve treatment outcomes and improve the quality of life for patients with this debilitating condition.
Navigating PAD Treatment: Exploring New Options for Improved Outcomes
PAD is a common and often challenging condition to manage. This study underscores the importance of exploring new treatment options to improve outcomes and reduce the risk of complications. Paclitaxel-coated balloons offer a potentially more effective and safe approach to treating femoropopliteal artery disease, providing a glimmer of hope for patients seeking better treatment options. As always, consultation with a healthcare professional is crucial to determine the best treatment course for each individual.
Dr.Camel's Conclusion
This study, like a desert oasis providing life-sustaining water, unveils the potential of paclitaxel-coated balloons in treating femoropopliteal artery disease. The improved patency rates and safety profile offer a promising new path for those seeking effective treatment for PAD. This research is a testament to the ongoing quest for innovative therapies to improve the lives of patients facing this challenging condition.
Date :
- Date Completed 2015-07-16
- Date Revised 2022-04-08
Further Info :
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