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The effect of sexually transmitted co-infections on HIV viral load amongst individuals on antiretroviral therapy: a systematic review and meta-analysis.

Author: BellanSteven E, ChampredonDavid, DelvaWim, DushoffJonathan, HuntSpencer, ShiChyun-Fung, SmiejaMarek

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Antiretroviral therapy (ART) can significantly reduce the spread of HIV. While testing and treatment programs are being promoted to reduce HIV transmission, it's unclear how other sexually transmitted infections (STIs), which increase the risk of spreading HIV in untreated people, might affect the effectiveness of treatment as a prevention strategy.
Paper Details　
Original Abstract of the Article :
Antiretroviral therapy (ART) markedly reduces HIV transmission, and testing and treatment programs have been advocated as a method for decreasing transmission at the population level. Little is known, however, about the extent to which sexually transmitted infections (STIs), which increase the HIV i...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486691/

データ提供：米国国立医学図書館（NLM）

STIs and HIV: Exploring the Sands of Co-Infection

The [treatment of HIV] is a critical part of [HIV prevention] efforts, but [sexually transmitted infections (STIs)] can complicate the picture. This [systematic review and meta-analysis] investigates the [impact of STIs on HIV viral load] among [individuals on antiretroviral therapy]. The authors raise a crucial question: [Do STIs decrease the effectiveness of treatment as prevention]? This is a vital question as [ART] is crucial to [reduce HIV transmission], and understanding the [influence of STIs] is essential for [effective public health strategies].

STIs: A Potential Obstacle to HIV Prevention

This review highlights the [potential impact] of [STIs] on [HIV viral load] and [transmission]. It suggests that [STIs] might [reduce the effectiveness] of [treatment as prevention] strategies. Further research is needed to [fully understand this complex interaction].

Navigating the Desert of STIs: Considerations for Patients

It is essential to [practice safe sex] and [get tested regularly] for [STIs]. [Early diagnosis and treatment] are crucial for [managing STIs] and [preventing complications] for both [individual health] and [public health].

Dr.Camel's Conclusion

The desert of HIV is full of challenges, and STIs can be like shifting sand dunes, making the journey more difficult. This review highlights the [importance of addressing STIs] in [HIV prevention] efforts. We hope that future research will lead to [a better understanding] of this complex interaction and [more effective strategies] for [combating the spread of HIV].

Date :
  1. Date Completed 2016-05-02
  2. Date Revised 2019-03-18
Further Info :

Pubmed ID

26123030

DOI: Digital Object Identifier

PMC4486691

SNS
PICO Info
in preparation
Languages

English

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