Differential glatiramer acetate treatment persistence in treatment-naive patients compared to patients previously treated with interferon.

Author: ChamorroBeatriz, Fernández-FournierMireya, Martínez-SánchezPatricia, PuertasInmaculada, Tallón-BarrancoAntonio

Paper Details 
Original Abstract of the Article :
In the treatment of multiple sclerosis, a change of therapy is considered after treatment failure or adverse events. Although disease modifying drugs' (DMD) efficacy and side effects have been fully analysed in clinical trials, the effects of previous therapy use are less well studied. We aimed to s...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545781/

データ提供:米国国立医学図書館(NLM)

Glatiramer Acetate Treatment Persistence in Multiple Sclerosis

The search for effective treatments for multiple sclerosis (MS) is a journey across a vast and challenging desert. This study focuses on medication persistence with glatiramer acetate (GA), a common treatment for MS. The researchers investigated whether previous treatment with interferon (IFN) impacted persistence with GA in patients with MS.

Treatment History Influences Medication Persistence

The study found that treatment-naive patients, those who had not previously received IFN treatment, had significantly higher persistence with GA compared to patients who had previously been treated with IFN. This suggests that prior IFN treatment may influence a patient's likelihood of continuing GA therapy. The study suggests that the underlying reasons for this difference may be related to different disease characteristics or individual patient factors.

Tailoring Treatment for Optimal Outcomes

This research highlights the importance of considering a patient's treatment history when developing treatment plans for MS. By understanding the factors that influence medication persistence, healthcare professionals can tailor treatments to maximize their effectiveness and minimize interruptions.

Dr.Camel's Conclusion

This study provides valuable insights into the complexities of medication persistence in MS. It emphasizes the need for individualized treatment plans that consider the unique experiences and needs of each patient. Like a wise camel guiding a caravan through a difficult terrain, healthcare professionals must navigate the landscape of MS treatment with care and attention to detail.

Date :
  1. Date Completed 2016-04-14
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

26286576

DOI: Digital Object Identifier

PMC4545781

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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