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Interventions for dialysis patients with hepatitis C virus (HCV) infection.

Author: NairSreekumar, PaiGanesh, PrabhuRavindra A, ReddyNageswara P, SuvarnaDeepak

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Hepatitis C virus (HCV) infection is common in people with chronic kidney disease (CKD) on dialysis, causing liver problems and increasing the risk of death. While treatment with interferon can be successful, about 39% of patients don't respond, and 20% have to stop treatment due to side effects. This study aimed to review the research on treating HCV infection in dialysis patients, examining the effectiveness and potential risks of various treatments.
Paper Details　
Original Abstract of the Article :
Hepatitis C virus (HCV) infection is common in chronic kidney disease (CKD) patients on dialysis, causes chronic liver disease, increases mortality and impacts kidney transplant outcomes. Sustained response to the preferred treatment with standard or pegylated (PEG) interferon is seen in 39% with si...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208657/

データ提供：米国国立医学図書館（NLM）

Hepatitis C: A Silent Storm in the Desert of Dialysis

Chronic kidney disease (CKD) patients on dialysis often face a formidable foe - hepatitis C virus (HCV) infection. This silent storm can wreak havoc on the liver, leading to a cascade of complications and increasing mortality. In this harsh landscape of chronic illness, current treatments for HCV infection are a beacon of hope, but they come with their own challenges. The authors of this review meticulously combed through the scientific literature to assess the effectiveness and safety of various interventions for HCV infection in dialysis patients.

They highlight the fact that, despite advances in treatment, the response rate to standard or pegylated interferon therapy remains modest, with a significant proportion of patients experiencing side effects that necessitate treatment discontinuation. The review presents a comprehensive overview of available interventions, providing valuable insights for clinicians navigating this complex terrain.

Navigating the Desert: A Guide for HCV Treatment

This review serves as a vital compass for healthcare professionals navigating the complex landscape of HCV treatment in dialysis patients. It underscores the need for individualized approaches, taking into account the unique challenges faced by these individuals. Furthermore, it emphasizes the importance of continued research to develop safer and more effective therapies for this chronic condition.

Living with CKD and HCV: A Desert Oasis

Living with CKD and HCV is like navigating a vast desert, where every resource is precious and every challenge demands resilience. This review offers a ray of hope, emphasizing the importance of early diagnosis and treatment, along with close monitoring of patients' health. By understanding the intricacies of HCV infection and the available interventions, we can empower patients to take control of their health and find a path towards a healthier future.

Dr. Camel's Conclusion

This review provides a valuable roadmap for managing HCV infection in dialysis patients, highlighting the challenges and opportunities in this complex field. It underscores the need for individualized treatment approaches, continued research into novel therapies, and ongoing support for patients navigating this difficult terrain. Just as a desert traveler relies on a dependable guide, patients with CKD and HCV need a skilled and compassionate healthcare team to support them on their journey towards better health.

Date :
  1. Date Completed 2016-03-01
  2. Date Revised 2023-04-26
Further Info :

Pubmed ID

26287983

DOI: Digital Object Identifier

PMC9208657

Related Literature

Article Analysis
・Effective treatment of hepatitis c
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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