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Efficacy and safety of topical difluprednate in persistent diabetic macular edema.

Author: KaurSavleen, SachdevNishant, SinghSwati, YangzesSonam

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Difluprednate ophthalmic emulsion 0.05% was found to be effective in reducing persistent diabetic macular edema. In a study of 20 patients, visual acuity increased by two lines and central retinal thickness decreased by 18.4% after 3 months of treatment. However, 20% of patients experienced raised intraocular pressure as a side effect.
Paper Details　
Original Abstract of the Article :
To evaluate the efficacy and safety of treatment of diabetic macular edema (persistent type) with difluprednate ophthalmic emulsion 0.05 % (off label use). 20 patients with persistent diabetic macular edema were enrolled. In all subjects, more than 4 months had passed since prior treatment. All pati...See full text at original site
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引用元：
https://doi.org/10.1007/s10792-015-0121-3

データ提供：米国国立医学図書館（NLM）

Topical Difluprednate for Persistent Diabetic Macular Edema

Diabetic macular edema (DME) is a serious complication of diabetes that can affect vision. This study investigated the efficacy and safety of topical difluprednate, a corticosteroid, in treating persistent DME. The authors found that difluprednate significantly reduced retinal thickness and improved visual acuity in patients with persistent DME, suggesting its potential as an adjuvant therapy. However, the study also highlighted the potential side effect of raised intraocular pressure, limiting its use in non-steroid responders.

A Potential Weapon Against Diabetic Macular Edema

This study sheds light on the potential of topical difluprednate in treating persistent DME, offering a potential weapon against this vision-threatening condition. It's like discovering a hidden oasis in the desert of DME research, providing a source of relief and hope for patients struggling with this complication.

Navigating the Treatment of Diabetic Macular Edema

Diabetic macular edema can be a challenging condition, like navigating a treacherous desert landscape. This study offers valuable insights into potential treatment options, highlighting the benefits and limitations of topical difluprednate. It's a reminder that careful consideration of potential risks and benefits is crucial when making treatment decisions.

Dr.Camel's Conclusion

This study explores the use of topical difluprednate in treating persistent diabetic macular edema, offering a potential solution for improving visual function and reducing retinal thickness. While the study highlights the potential for this treatment, it also cautions about the risk of raised intraocular pressure. It's a reminder that the desert of medical research is vast and complex, requiring careful navigation and consideration of potential side effects when selecting treatment options for challenging conditions like DME.

Date :
  1. Date Completed 2017-03-31
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

26296375

DOI: Digital Object Identifier

10.1007/s10792-015-0121-3

SNS
PICO Info
in preparation
Languages

English

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