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Pharmacokinetics of Glycopyrronium Following Repeated Once-Daily Inhalation in Healthy Chinese Subjects.
Author: HaraHisanori, HouJie, MachineniSurendra, RenShuang, SechaudRomain, TanXuemei, TillmannHanns-Christian, ZhaoRong
Original Abstract of the Article :
BACKGROUND AND OBJECTIVES: Glycopyrronium is a once-daily long-acting muscarinic antagonist for the maintenance treatment of patients with chronic obstructive pulmonary disease. This study assessed the pharmacokinetics of inhaled glycopyrronium 50 µg once-daily for 14 days in healthy Chinese subject...See full text at original site
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引用元:
https://doi.org/10.1007/s13318-015-0300-7
データ提供:米国国立医学図書館(NLM)
Glycopyrronium: A Long-Acting Muscarinic Antagonist for COPD Management
This study investigates the pharmacokinetic profile of glycopyrronium, a long-acting muscarinic antagonist used for managing chronic obstructive pulmonary disease (COPD). COPD is a chronic lung disease that causes airflow obstruction and breathing difficulties. Glycopyrronium works by blocking the action of acetylcholine, a neurotransmitter that constricts the airways. Understanding the pharmacokinetics of glycopyrronium is crucial for optimizing its dosage and ensuring its efficacy in COPD treatment.
Glycopyrronium: A Controlled Release of Relief for COPD Patients
The study found that glycopyrronium is rapidly absorbed into the bloodstream after inhalation and remains effective for a prolonged period. The researchers also found that repeated daily doses of glycopyrronium were well-tolerated and did not lead to significant accumulation in the body, making it a safe and effective long-term treatment option for COPD patients. The study also compared the pharmacokinetic profile of glycopyrronium in Chinese subjects to previous studies in non-Chinese populations, finding no significant ethnic differences in its absorption and elimination.
Navigating the Desert of COPD: A Long-Acting Solution
This study provides valuable insights into the pharmacokinetics of glycopyrronium, a long-acting muscarinic antagonist used in COPD management. It highlights the safety and efficacy of this medication, offering COPD patients a long-term solution for managing their symptoms and improving their quality of life. Understanding the pharmacokinetic profile of glycopyrronium is crucial for healthcare providers to make informed decisions about its dosage and ensure its optimal effectiveness for individual patients.
Dr.Camel's Conclusion
Imagine a desert traveler with COPD, struggling to breathe through the suffocating sandstorms. This study reveals the benefits of glycopyrronium, a long-acting medication that provides a sustained oasis of relief for COPD patients, allowing them to navigate the desert with greater ease and comfort.
Date :
- Date Completed 2018-01-26
- Date Revised 2022-12-07
Further Info :
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