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Gene therapy with recombinant adeno-associated vectors for neovascular age-related macular degeneration: 1 year follow-up of a phase 1 randomised clinical trial.
Author: BlumenkranzMark S, ChalbergThomas W, ConstableIan J, Degli-EspostiMariapia A, FrenchMartyn A, LaiChooi-May, MagnoAaron L, PierceCora M, RakoczyElizabeth P, SchwartzSteven D, WikstromMatthew E
Original Abstract of the Article :
Neovascular, or wet, age-related macular degeneration causes central vision loss and represents a major health problem in elderly people, and is currently treated with frequent intraocular injections of anti-VEGF protein. Gene therapy might enable long-term anti-VEGF therapy from a single treatment....See full text at original site
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引用元:
https://doi.org/10.1016/S0140-6736(15)00345-1
データ提供:米国国立医学図書館(NLM)
Gene Therapy for Wet Age-Related Macular Degeneration: A Promising New Approach
The debilitating condition of [wet age-related macular degeneration] is a major public health concern, particularly among elderly populations. Current treatment involves frequent [intraocular injections of anti-VEGF protein], which can be burdensome for patients. This study explores the potential of [gene therapy] using [rAAV.sFLT-1] as a long-term solution for wet AMD. The study focused on evaluating the safety of a single subretinal injection of rAAV.sFLT-1 in a phase 1 randomized clinical trial.
Safety and Potential of Gene Therapy
The study findings suggest that [rAAV.sFLT-1] is a safe treatment option for wet AMD. While further studies are needed to assess its efficacy, this research offers a promising new approach to managing this debilitating condition. This research presents a hopeful approach for the millions suffering from wet AMD. The potential for long-term, sustained treatment from a single injection could significantly improve the quality of life for those affected.
Hope for the Future of Vision Care
This research represents a step towards developing a more effective and convenient treatment option for wet AMD. It is a testament to the progress being made in the field of [gene therapy] and offers hope for the future of vision care. It's like finding a hidden oasis in the desert, providing a source of relief and hope for a parched and challenging journey.
Dr.Camel's Conclusion
This research is a testament to the power of innovation and the relentless pursuit of better treatment options. It's like a camel caravan venturing into unexplored territory, seeking new paths to healing and well-being. This study reminds us that the future of medicine is bright, and with perseverance and ingenuity, we can continue to push the boundaries of what is possible.
Date :
- Date Completed 2016-01-04
- Date Revised 2022-04-08
Further Info :
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