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Depressor effect of chymase inhibitor in mice with high salt-induced moderate hypertension.
Author: DevarajanSankar, HabeShigehisa, MiuraShin-ichiro, NishiyamaAkira, SakuKeijiro, UeharaYoshinari, UrataHidenori, YahiroEiji
Original Abstract of the Article :
The aim of the present study was to determine whether long-term high salt intake in the drinking water induces hypertension in wild-type (WT) mice and whether a chymase inhibitor or other antihypertensive drugs could reverse the increase of blood pressure. Eight-week-old male WT mice were supplied w...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元:
https://doi.org/10.1152/ajpheart.00721.2014
データ提供:米国国立医学図書館(NLM)
Investigating the Role of Chymase in Salt-Sensitive Hypertension
The study of [hypertension] is an ongoing field of research, seeking to understand the underlying mechanisms and develop effective treatment strategies. This research explores the role of [chymase] in the development of [salt-sensitive hypertension]. The authors utilize a [mouse model] to investigate the effects of long-term high salt intake on blood pressure and the involvement of [chymase] in this process. The study sheds light on the potential therapeutic benefits of [chymase inhibitors] in managing [salt-sensitive hypertension].
Chymase Plays a Key Role in Salt-Sensitive Hypertension
This research reveals that [chymase] plays a significant role in the development of [salt-sensitive hypertension]. The study found that long-term high salt intake in mice led to an increase in blood pressure and that a [chymase inhibitor] effectively suppressed this elevation. The findings suggest that [chymase] may be a potential target for the development of new therapies for [salt-sensitive hypertension].
Managing Salt Intake for Cardiovascular Health
This research emphasizes the importance of managing salt intake for maintaining cardiovascular health. The authors highlight the potential role of [chymase] in the development of [salt-sensitive hypertension], emphasizing the need to consider the impact of dietary factors on cardiovascular health. This research underscores the need for a balanced diet, low in sodium, to promote cardiovascular well-being.
Dr.Camel's Conclusion
This research adds to our understanding of the mechanisms underlying [salt-sensitive hypertension], revealing the crucial role of [chymase] in this process. The findings suggest that [chymase inhibitors] may be a promising avenue for developing novel therapies for [salt-sensitive hypertension].
Date :
- Date Completed 2016-04-11
- Date Revised 2020-09-30
Further Info :
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