Definition of the effective dose of the converting-enzyme inhibitor benazepril.

Author: WhalenJ J

Paper Details 
Original Abstract of the Article :
Benazepril was shown in preclinical studies to be a potent and specific inhibitor of angiotensin-converting enzyme with a benign toxicologic profile. Its onset and duration of action and the dose-response relationship of its antihypertensive effect have been evaluated. The results of these studies s...See full text at original site
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引用元:
https://doi.org/10.1016/0002-8703(89)90762-x

データ提供:米国国立医学図書館(NLM)

Benazepril: A Targeted Approach to Blood Pressure Control

The search for safe and effective treatments for hypertension, a common and potentially serious health condition, is a constant pursuit in the field of medicine. This research examines the effectiveness and safety of the angiotensin-converting enzyme (ACE) inhibitor benazepril in controlling blood pressure.

The authors conducted several studies to evaluate the dose-response relationship of benazepril's antihypertensive effect. They found that 20 mg of benazepril once daily significantly lowered blood pressure, achieving clinically significant improvement compared to placebo. Doses as low as 10 mg once daily may be effective in some patients. The study also found that benazepril had minimal effects on blood chemistry, with the exception of a slight rise in serum potassium.

Benazepril: A Valuable Tool in Blood Pressure Management

This research provides valuable information about the effectiveness and safety of benazepril in managing hypertension. The findings suggest that benazepril is a potent and specific inhibitor of ACE, effectively lowering blood pressure with a generally benign toxicologic profile. The study's findings highlight the need for individualized dosing strategies to optimize blood pressure control while minimizing potential side effects.

Navigating the Desert of Hypertension Treatment

For patients with hypertension, this research emphasizes the importance of consulting with a healthcare professional to determine the most appropriate treatment strategy. Benazepril, like a well-equipped camel navigating the desert of hypertension, offers a reliable and safe method for controlling blood pressure. Careful monitoring and individualized dosing are key to achieving optimal blood pressure management and maintaining overall health.

Dr.Camel's Conclusion

This study, like a well-traveled path through the desert of hypertension research, offers valuable insights into the effectiveness and safety of benazepril. The findings suggest that benazepril is a potent and specific inhibitor of ACE, offering a reliable and safe method for controlling blood pressure with minimal side effects. Individualized dosing strategies and careful monitoring are essential for achieving optimal blood pressure management and maintaining overall health.

Date :
  1. Date Completed 1989-04-04
  2. Date Revised 2019-06-26
Further Info :

Pubmed ID

2645756

DOI: Digital Object Identifier

10.1016/0002-8703(89)90762-x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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