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Lithium in the Acute Treatment of Bipolar I Disorder: A Double-Blind, Placebo-Controlled Study.

Author: AnandRavinder, ClemonsTraci E, DelBelloMelissa, FindlingRobert L, FrazierJean A, KafantarisVivian, KowatchRobert A, LinglerJacqui, MartzKaren, McNamaraNora K, PavuluriMani N, RobbAdelaide, RowlesBrieana M, RynnMoira, SchefferRussell, Taylor-ZapataPerdita

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

This study found that lithium was superior to placebo in reducing manic symptoms in children with bipolar disorder type 1. Lithium was well tolerated and did not cause weight gain.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Lithium is a benchmark treatment for bipolar disorder in adults. Definitive studies of lithium in pediatric bipolar I disorder (BP-I) are lacking. METHODS: This multicenter, randomized, double-blind, placebo-controlled study of pediatric participants (ages 7-17 years) with BP-I/manic or...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621794/

データ提供：米国国立医学図書館（NLM）

Lithium: A Beacon of Hope for Pediatric Bipolar I Disorder

Bipolar disorder, a mental health condition characterized by mood swings, can be as challenging to manage as navigating a desert of fluctuating emotions. This research investigates the use of lithium in the treatment of pediatric bipolar I disorder, seeking to find a way to stabilize mood and improve quality of life for young patients. The study examines the effectiveness and safety of lithium in this specific population, aiming to provide a more stable and predictable path for these young individuals.

Lithium: A Stabilizing Force for Pediatric Bipolar Disorder

The research suggests that lithium might be an effective treatment for reducing manic symptoms in pediatric patients with bipolar I disorder. This finding offers hope for these young individuals, much like finding a steady oasis in a desert of emotional turmoil. The study highlights the importance of finding safe and effective treatments for bipolar disorder in children and adolescents, emphasizing the need for continued research and development of appropriate therapies.

Navigating Pediatric Bipolar Disorder: Finding Stability and Hope

This research underscores the importance of finding effective treatments for bipolar disorder in young individuals. It's a journey of discovery, much like a desert explorer seeking a path to a more stable and fulfilling life. The study provides valuable insights into the potential of lithium, offering hope for a future where young people with bipolar disorder can experience a more stable and fulfilling life.

Dr.Camel's Conclusion

This research represents a significant step forward in the understanding and treatment of pediatric bipolar disorder. It's a journey of hope, much like finding a safe haven in a desert of emotional turmoil. I, Dr. Camel, believe that this study will inspire continued research and development of effective treatments for bipolar disorder in children and adolescents, offering a brighter future for these young individuals.
Date :
  1. Date Completed 2016-02-11
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

26459650

DOI: Digital Object Identifier

PMC4621794

Related Literature

Article Analysis
・Effective treatment of bipolar disorder
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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