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Effects of Nephrolithiasis on Serum DNase (Deoxyribonuclease I and II) Activity and E3 SUMO-Protein Ligase NSE2 (NSMCE2) in Malaysian Individuals.

Author: GhazaliHamid, MehdeAtheer Awad, MehdiWesen Adel, RahmanAzlina Abd, RausRaha Ahmed, YusofFaridah

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study explored the potential of DNase I/II activity and E3 SUMO-protein ligase NSE2 as biomarkers for kidney damage in nephrolithiasis patients.
Paper Details　
Original Abstract of the Article :
Nephrolithiasis is one of the most common disorders of the urinary tract. The aim of this study was to examine a possible relationship between DNase I/II activity and E3 SUMO-protein ligase NSE2 in the sera of nephrolithiasis patients to evaluate the possibility of a new biomarker for evaluating kid...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/26464253

データ提供：米国国立医学図書館（NLM）

Exploring Potential Biomarkers for Nephrolithiasis

Nephrolithiasis, a common condition affecting the [urinary tract], can lead to [kidney damage]. This study explores the potential of [DNase I/II activity and E3 SUMO-protein ligase NSE2] as [biomarkers] for evaluating kidney damage in patients with nephrolithiasis.

Potential Biomarkers for Kidney Damage

The study examined the levels of these [enzymes] in the [sera] of patients with nephrolithiasis, investigating their potential association with [kidney damage]. While the study results require further investigation, they suggest that these [enzymes] could serve as valuable [biomarkers] for assessing the severity of kidney damage in nephrolithiasis patients.

Uncovering New Tools for Kidney Health

Dr. Camel sees this research as a step towards a clearer understanding of the mechanisms underlying [kidney damage] in nephrolithiasis. Just as a camel uses its keen senses to navigate the desert, researchers are using their knowledge to uncover new tools for diagnosing and treating kidney disease.

Dr. Camel's Conclusion

This study sheds light on potential biomarkers for nephrolithiasis, opening new doors for early diagnosis and targeted treatment. Further research is needed to validate these findings and determine their clinical utility.

Date :
  1. Date Completed 2016-02-25
  2. Date Revised 2018-06-08
Further Info :

Pubmed ID

26464253

DOI: Digital Object Identifier

S0895-3988(15)30091-X

Related Literature

Article Analysis
・Effects of dnase
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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