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Managements of recurrent hepatocellular carcinoma after liver transplantation: A systematic review.

Author: AzoulayDaniel, CarraMaria Clotilde, LandiFilippo, de'AngelisNicola

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This study reviewed the efficacy and safety of treatments for recurrent hepatocellular carcinoma in patients who had undergone liver transplantation. The study found that recurrence rates are high and overall survival is poor. The most effective treatments were surgical resection for localized recurrence and Sorafenib for systemic spread of the cancer.
Paper Details　
Original Abstract of the Article :
AIM: To investigate the efficacy (survival) and safety of treatments for recurrent hepatocellular carcinoma (HCC) in liver transplantation (LT) patients. METHODS: Literature search was performed on available online databases without a time limit until January 2015. Clinical studies describing survi...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607916/

データ提供：米国国立医学図書館（NLM）

Navigating the Challenges of Recurrent Hepatocellular Carcinoma

This study explores the complex and challenging world of [hepatocellular carcinoma (HCC)] recurrence after liver transplantation (LT). It's like a caravan facing unexpected sandstorms, navigating the difficult journey of managing a recurrent disease. The researchers conducted a comprehensive review of literature, examining the efficacy and safety of various treatments for recurrent HCC in LT patients. They found that HCC recurrence after LT is a significant concern, with a median time to recurrence of 13 months. The study also highlighted the importance of early detection and aggressive treatment strategies for improving survival rates.

Finding Hope in the Face of Recurrence

This study is like finding a guiding star in the desert, offering hope for patients facing recurrent HCC. The researchers have meticulously compiled and analyzed data on various treatment options, providing valuable insights for healthcare providers in managing this challenging condition.

Living with Liver Disease

Hepatocellular carcinoma is a serious liver cancer. It's important to consult with a healthcare professional for proper diagnosis, treatment, and management of this condition.

Dr.Camel's Conclusion

This study is a poignant reminder of the complexity and challenges faced by patients with recurrent HCC. The researchers have shed light on the need for a multidisciplinary approach to managing this condition, involving early detection, aggressive treatment, and comprehensive care. I commend their efforts in compiling valuable information that can guide healthcare providers and empower patients in navigating this challenging journey.
Date :
  1. Date Completed 2016-10-05
  2. Date Revised 2022-04-19
Further Info :

Pubmed ID

26494973

DOI: Digital Object Identifier

PMC4607916

Related Literature

Article Analysis
・Effective treatment of liver transplantation
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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