The dose effects of zolpidem on the sleep of healthy normals.

Author: KoshorekG, LamphereJ, MerlottiL, RoehrsT, RothT, ZorickF

Paper Details 
Original Abstract of the Article :
This study determined the dose effects of zolpidem in 12 healthy males with normal sleep patterns. Subjects spent 7 weeks, 3 consecutive nights per week, in the laboratory and had a 4-night washout between treatments. The first week was a screening and adaptation week. Then subjects received zolpide...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/2651493

データ提供:米国国立医学図書館(NLM)

Zolpidem: Investigating the Dose Effects on Sleep

The world of sleep research is a vast and mysterious desert, where researchers are constantly seeking to understand the intricate mechanisms that govern our nightly slumber. This study, like a team of intrepid explorers venturing into this uncharted territory, investigates the dose effects of zolpidem, a medication commonly used to treat insomnia. The researchers, armed with sophisticated sleep monitoring techniques, explore the impact of different zolpidem doses on the sleep patterns of healthy individuals.

Zolpidem's Dose-Dependent Effects on Sleep

The study's findings, like a map revealing the hidden pathways of sleep, demonstrate the dose-dependent effects of zolpidem on various sleep parameters. The researchers discovered that zolpidem, like a sleep-inducing elixir in the desert, effectively shortened the time it took to fall asleep and increased total sleep time at doses of 7.5 mg and higher. This discovery, like a refreshing oasis in the desert of insomnia, provides valuable insights into the potential benefits of zolpidem for improving sleep quality. However, they also found that higher doses of zolpidem, particularly 20 mg, reduced REM sleep, highlighting the importance of finding the optimal dose for each individual.

Navigating the Landscape of Sleep Disorders

The study's findings, like a compass guiding us through the complex landscape of sleep disorders, underscore the importance of individualizing treatment approaches based on the specific needs of each patient. The researchers' careful investigation of the dose-dependent effects of zolpidem, like a caravan traversing a vast and unforgiving desert, reminds us that the journey to better sleep requires a thoughtful and personalized approach. Remember, just as a desert ecosystem is constantly evolving, our understanding of sleep is also evolving. It is crucial to stay informed about new treatments and to work with healthcare professionals to develop the most effective treatment plan for each individual.

Dr. Camel's Conclusion

This study, like a caravan crossing a vast and unforgiving desert, sheds light on the dose-dependent effects of zolpidem on sleep. The researchers' findings, like a well-hidden oasis, demonstrate the potential of zolpidem to improve sleep quality while highlighting the importance of finding the optimal dose for each individual. Remember, just as a desert ecosystem relies on balance and harmony, achieving restful sleep requires a careful consideration of the individual's needs and the potential benefits and risks of different medications.

Date :
  1. Date Completed 1989-06-01
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

2651493

DOI: Digital Object Identifier

2651493

Related Literature

SNS
PICO Info
in preparation
Languages

English

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