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Comparative trial of two antihistamines, mequitazine and brompheniramine.

Author: BlamoutierJ

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Mequitazine and brompheniramine, both antihistamines, were compared for their efficacy and tolerability in treating allergic disorders. Mequitazine was found to be at least as effective as brompheniramine, but with significantly less drowsiness. Few other side effects were reported.
Paper Details　
Original Abstract of the Article :
A double-blind trial was carried out in 48 patients with allergic disorders to compare the efficacy and tolerance of mequitazine and brompheniramine. Patients received either 10 mg mequitazine or 24 mg brompheniramine daily, divided into 2 doses, for 14 days. The results, analyzed from patients' ans...See full text at original site
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引用元：
https://doi.org/10.1185/03007997809111899

データ提供：米国国立医学図書館（NLM）

Comparative Trial of Two Antihistamines, Mequitazine and Brompheniramine

This double-blind trial compared the efficacy and tolerance of two antihistamines, mequitazine and brompheniramine, in patients with allergic disorders. The study involved 48 patients who received either 10 mg of mequitazine or 24 mg of brompheniramine daily for 14 days. The results showed that mequitazine was at least as effective as brompheniramine in alleviating allergic symptoms and caused significantly less drowsiness throughout the trial period. The study found that mequitazine was a well-tolerated medication with few side effects.

Mequitazine Emerges as a Potential Alternative for Allergic Relief

The trial demonstrated that mequitazine was as effective as brompheniramine in managing allergic symptoms, but with the added benefit of causing significantly less drowsiness. This finding suggests that mequitazine could be a suitable alternative for patients seeking relief from allergic symptoms without experiencing the sedative side effects often associated with other antihistamines.

Navigating the Landscape of Allergy Relief: Finding the Right Fit

This research underscores the importance of considering individual patient needs and preferences when choosing antihistamines. The study highlights the potential benefits of mequitazine as a less sedating alternative to brompheniramine, offering patients a more comfortable and effective treatment option for their allergic symptoms. As a wise old camel, I’ve learned that navigating the vast expanse of the medical field requires a keen awareness of the nuances and specific needs of each individual. Remember, finding the right solution for each patient often involves a thoughtful and individualized approach.

Dr.Camel's Conclusion

This comparative trial offers a valuable comparison of two antihistamines, revealing mequitazine as a potentially better alternative for patients seeking relief from allergic symptoms without experiencing significant drowsiness. The study highlights the importance of considering individual needs and preferences when choosing medications. Remember, the journey to optimal health involves understanding the unique characteristics of each individual and finding the best possible solution for their specific needs.
Date :
  1. Date Completed 1978-08-28
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

26516

DOI: Digital Object Identifier

10.1185/03007997809111899

Related Literature

Article Analysis
・Side Effects of brompheniramine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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